Pablo E.Tomatis
机构: Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET-UNR)
每年引用次数
引用次数
引用: 628
H-指数: 10
I10-指数 : 11
出版物: 20
Mimicking natural evolution in metallo-β-lactamases through second-shell ligand mutations
P. E. Tomatis , R. M. Rasia , L. Segovia , A. J. Vila
Proceedings of the National Academy of Sciences of the United States of America 102 ( 39) 13761 -13766
75
2005
Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility.
P. E. Tomatis , S. M. Fabiane , F. Simona , P. Carloni
Proceedings of the National Academy of Sciences of the United States of America 105 ( 52) 20605 -20610
83
2008
Mutations in sigma 70 transcription factor improves expression of functional eukaryotic membrane proteins in Escherichia coli.
Pablo Emiliano Tomatis , Marco Schütz , Elina Umudumov , Andreas Plückthun
Scientific Reports 9 ( 1) 2483 -2483
4
2019
Efecto de la vacunación sobre la transmisión intradomiciliaria del SARS-COV-2, provincia de Santa Fe, Argentina, 2021
Lucas Fernando De Candia , Natalia Santucci , Andrés Alloatti , Julieta Barchiesi
Revista Argentina de Salud Pública 13 28 -28
1
2021
B-lactamase remodeling and evolution of collateral resistance in hypermutator Pseudomonas aeruginosa upon long-term antibiotic therapy
Claudia Antonella Colque , Pablo Emiliano Tomatis , Andrea Georgina Albarracín Orio , Gina Dotta
Cold Spring Harbor
2021
BioF is a novel B2 metallo‐β‐lactamase from Pseudomonas sp. isolated from an on‐farm biopurification system
Juan Hilario Cafiero , María Carla Martini , Mauricio Javier Lozano , Carolina Vacca
Environmental Microbiology 24 ( 3) 1247 -1262
2022
WS13. 06 Development of antibiotic resistance reveals diverse evolutionary pathways to face the complex and dynamic environment of a long-term treated patient
CA Colque , PE Tomatis , AG Albarracín Orio , G Dotta
Journal of Cystic Fibrosis 21 S26 -S26
2022
Development of antibiotic resistance reveals diverse evolutionary pathways to face the complex and dynamic environment of a long-term treated patient
CA Colque , PE Tomatis , Albarracín Orio AG , G Dotta
2021
Metallo-β-lactamases withstand low Zn(II) conditions by tuning metal-ligand interactions
Javier M González , María-Rocío Meini , Pablo E Tomatis , Francisco J Medrano Martín
Nature Chemical Biology 8 ( 8) 698 -700
39
2012
Engineered mononuclear variants in Bacillus cereus metallo-β-lactamase BcII are inactive
Luciano A Abriata , Lisandro J González , Leticia I Llarrull , Pablo E Tomatis
Biochemistry 47 ( 33) 8590 -8599
32
2008
Engineered Mononuclear Variants in Bacillus cereus Metallo--lactamase BcII Are Inactive
Luciano A Abriata , Lisandro J González , Leticia I Llarrull , Pablo E Tomatis
Longitudinal evolution of the Pseudomonas-derived cephalosporinase (PDC) structure and activity in a cystic fibrosis patient treated with β-lactams
Claudia A Colque , Andrea G Albarracin Orio , Pablo E Tomatis , Gina Dotta
Mbio 13 ( 5) e01663 -22
8
2022
The biochemistry and enzymology of zinc enzymes
Guillermo Bahr , Pablo E Tomatis , Alejandro J Vila
Elsevier 231 -267
2
2023
Sequence-function-stability relationships in proteins from datasets of functionally annotated variants: The case of TEM β-lactamases
Luciano A Abriata* , Merijn LM Salverda , Pablo E Tomatis , (* = corresponding author)
FEBS Letters 586 ( 19) 3330 -3335
22
2012
Quantitative Description of a Protein Fitness Landscape Based on Molecular Features
María-Rocío Meini , Pablo E. Tomatis , Daniel M. Weinreich , Alejandro J. Vila
Molecular Biology and Evolution 32 ( 7) 1774 -1787
38
2015
Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory
Mariano M. González , Luciano A. Abriata , Pablo E. Tomatis , Alejandro J. Vila
Molecular Biology and Evolution 33 ( 7) 1768 -1776
34
2016
A minimalistic approach to identify substrate binding features in B1 Metallo-β-lactamases
Andrés A. Poeylaut-Palena , Pablo E. Tomatis , Andreas I. Karsisiotis , Christian Damblon
Bioorganic & Medicinal Chemistry Letters 17 ( 18) 5171 -5174
25
2007
Biochemical Characterization of Metallo-β-Lactamase VIM-11 from a Pseudomonas aeruginosa Clinical Strain
Patricia Marchiaro , Pablo E. Tomatis , María A. Mussi , Fernando Pasteran
Antimicrobial Agents and Chemotherapy 52 ( 6) 2250 -2252
23
2008
Analysis of Mesorhizobium loti glycogen operon: Effect of phosphoglucomutase (pgm) and glycogen synthase (glgA) null mutants on nodulation of Lotus tenuis
Viviana C. Lepek , Alejandra L. D'Antuono , Pablo E. Tomatis , Juan E. Ugalde
Molecular Plant-microbe Interactions 15 ( 4) 368 -375
21
2002
β-lactamase remodeling and evolution of collateral resistance in hypermutator Pseudomonas aeruginosa upon long-term antibiotic therapy
Tomatis Pe , Feliziani S , Vila Aj , Smania Am
bioRxiv
2021