Single-cell dissection of live human hearts in ischemic heart disease and heart failure reveals cell-type-specific driver genes and pathways

Suvi Linna-Kuosmanen , Eloi Schmauch , Kyriakitsa Galani , Carles A Boix
BioRxiv 2021.06. 23.449672 -2021.06. 23.449672

2
2021
Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease

Suvi Linna-Kuosmanen , Eloi Schmauch , Kyriakitsa Galani , Johannes Ojanen
Cell Reports Medicine 5 ( 5)

2024
The critical role of isomiRs in accurate differential expression analysis of miRNA-seq data

Eloi Schmauch , Yassine Attia , Pia Laitinen , Tiia A Turunen
bioRxiv 2024.03. 28.587190 -2024.03. 28.587190

2024
Targeting IL-1 controls refractory Pityriasis rubra pilaris

Eloi Schmauch , Yannik Severin , Xianying Xing , Aaron Mangold

2023
isomiRs-specific differential expression is the rule, not the exception: Are we missing hundreds of species in microRNA analysis?

Eloi Schmauch , Pia Laitinen , Tiia A Turunen , Mari-Anna Väänänen
bioRxiv 2021.12. 15.472814 -2021.12. 15.472814

2021
Deletion of the murine ortholog of human 9p21. 3 locus promotes atherosclerosis by increasing macrophage proinflammatory activity

Sanna Kettunen , Anna-Kaisa Ruotsalainen , Tiit Örd , Tuisku Suoranta
Frontiers in Cardiovascular Medicine 10 1113890 -1113890

4
2023
Cell-type-specific characterization of miRNA gene dynamics in immune cell subpopulations during aging and atherosclerosis disease development at single-cell resolution

Ana Hernandez de Sande , Tanja Turunen , Maria Bouvy-Liivrand , Tiit Örd
bioRxiv 2023.10. 09.561173 -2023.10. 09.561173

2023
Colchicine promotes atherosclerotic plaque stability independently of inflammation

Weizhen Li , Alexander Lin , Michael Hutton , Harkirat Dhaliwal
bioRxiv 2023.10. 03.560632 -2023.10. 03.560632

2023
Abstract P175: In Vitro Cholesterol Treatment Does Not Reproduce Smooth Muscle Cell Phenotypic Plasticity Observed In Vivo

Austin Conklin , Florencia Schlamp , Tiit Ord , Minna U Kaikkonen
Arteriosclerosis, Thrombosis, and Vascular Biology 41 ( Suppl_1) AP175 -AP175

2021
Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells

Ashik Jawahar Deen , Simone Adinolfi , Jouni Härkönen , Tommi Patinen
Redox Biology 69 103031 -103031

1
2024
Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease

Nicholas Darci-Maher , Marcus Alvarez , Uma Thanigai Arasu , Ilakya Selvarajan
EBioMedicine 92

7
2023
The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium

Andrey Anisimov , Shentong Fang , Karthik Amudhala Hemanthakumar , Tiit Örd
Nature cardiovascular research 2 ( 3) 307 -321

9
2023
Genetic regulation of human aortic smooth muscle cell gene expression and splicing predict causal coronary artery disease genes

Rédouane Aherrahrou , Dillon Lue , R Noah Perry , Yonathan Tamrat Aberra
bioRxiv 2022.01. 24.477536 -2022.01. 24.477536

3
2022
Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2 S, 4 R)-4-18F-Fluoroglutamine

Senthil Palani , Maxwell WG Miner , Jenni Virta , Heidi Liljenbäck
Frontiers in Immunology 13 821423 -821423

2
2022
Corrigendum: Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2 S, 4 R)-4-18F-Fluoroglutamine

Senthil Palani , Maxwell WG Miner , Jenni Virta , Heidi Liljenbäck
Frontiers in Immunology 13 902544 -902544

2022
Dissecting the polygenic basis of atherosclerosis via disease-associated cell state signatures

Tiit Örd , Tapio Lönnberg , Valtteri Nurminen , Aarthi Ravindran
The American Journal of Human Genetics 110 ( 5) 722 -740

8
2023
160. Truncated Vesicular Stomatitis Virus G-Protein Improves Baculovirus Transduction Efficiency In Vitro and In Vivo

Minna U Kaikkonen , Jani K Raty , Kari J Airenne , Thomas Wirth
Molecular Therapy 13 S63 -S63

105
2006
Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia

Pia Laitinen , Mari-Anna Väänänen , Ida-Liisa Kolari , Petri I Mäkinen
PLoS One 17 ( 3) e0265948 -e0265948

12
2022
Exploring the genetic basis of coronary artery disease using functional genomics

Maykel López Rodríguez , Uma Thanigai Arasu , Minna U Kaikkonen
Atherosclerosis 374 87 -98

7
2023