引用次数
引用: 40,448
H-指数: 103
I10-指数 : 362
出版物: 597
Tyrphostins inhibit FSH and cAMP mediated functions in rat ovarian granulosa cells: Possible involvement of tyrosine phosphorylation
R. Ziv , S. Gomberg-Malool , I. Posner , A. Levitzki
Journal of basic and clinical physiology and pharmacology 3 82 -83
2
1992
Stimulatory GTP regulatory unit Ns and the catalytic unit of adenylate cyclase are tightly associated: mechanistic consequences
H. Arad , J. P. Rosenbusch , A. Levitzki
Proceedings of the National Academy of Sciences of the United States of America 81 ( 21) 6579 -6583
43
1984
Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases.
M. Nagane , A. Levitzki , A. Gazit , W. K. Cavenee
Proceedings of the National Academy of Sciences of the United States of America 95 ( 10) 5724 -5729
330
1998
Signal transduction by a nondissociable heterotrimeric yeast G protein.
S. Klein , H. Reuveni , A. Levitzki
Proceedings of the National Academy of Sciences of the United States of America 97 ( 7) 3219 -3223
80
2000
Signal therapy for RAS-induced cancers in combination of AG 879 and PP1, specific inhibitors for ErbB2 and Src family kinases, that block PAK activation.
A Levitzki , E Manser , H Maruta , H He
Cancer Journal 7 ( 3) 191 -202
50
2001
Towards a PKB inhibitor
A Levitzki , H Reuveni , N Livnach , S Klein
Cellular & Molecular Biology Letters 06
2001
Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation.
I Ischenko , H Beug , A Levitzki , A Gazit
Cell Growth & Differentiation 8 ( 5) 481 -493
22
1997
Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program.
A Levitzki , A Gazit , I Posner , M Engel
Molecular Pharmacology 45 ( 4) 673 -683
110
1994
Effects of tyrphostins on the activated c-src protein in NIH/3T3 cells.
A Levitzki , W K Agbotounou , J Pierre , A Jacquemin-Sablon
Molecular Pharmacology 45 ( 5) 922 -931
22
1994
An anti-Ras cancer potential of PP1, an inhibitor specific for Src family kinases: in vitro and in vivo studies.
A Levitzki , H Maruta , H He , Y Hirokawa
Cancer Journal 6 ( 4) 243
24
2000
Tyrosine kinase blockers: new platelet activation inhibitors.
A Levitzki , S Levy-Toledano , A Eldor , F Grelac
Blood Coagulation & Fibrinolysis 1 ( 6) 713 -716
7
1990
Tyrphostins inhibit follicle-stimulating hormone-mediated functions in cultured rat ovarian granulosa cells.
S Gomberg-Malool , R Ziv , Y Re'em , I Posner
Endocrinology 132 ( 1) 362 -370
21
1993
Status of p53 in human cancer cells does not predict efficacy of CHK1 kinase inhibitors combined with chemotherapeutic agents.
S Zenvirt , N Kravchenko-Balasha , A Levitzki
Oncogene 29 ( 46) 6149 -6159
44
2010
Activation of phospholipase C in human B cells is dependent on tyrosine phosphorylation.
S Padeh , A Levitzki , A Gazit , G B Mills
Journal of Clinical Investigation 87 ( 3) 1114 -1118
54
1991
Beta subunit copurifies with GppNHp-activated adenylyl cyclase.
I Marbach , A Bar-Sinai , M Minich , A Levitzki
Journal of Biological Chemistry 265 ( 17) 9999 -10004
30
1990
Targeting melanoma with NT157 by blocking Stat3 and IGF1R signaling.
E Flashner-Abramson , S Klein , G Mullin , E Shoshan
Oncogene 35 ( 20) 2675 -2680
39
2016
Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling
E Sanchez-Lopez , E Flashner-Abramson , S Shalapour , Z Zhong
Oncogene 35 ( 20) 2634 -2644
82
2016
Kinetic model of the epidermal growth factor (EGF) receptor tyrosine kinase and a possible mechanism of its activation by EGF.
I Posner , M Engel , A Levitzki
Journal of Biological Chemistry 267 ( 29) 20638 -20647
59
1992
Selective interactions of transforming and normal abl proteins with ATP, tyrosine-copolymer substrates, and tyrphostins.
M Anafi , A Gazit , C Gilon , Y Ben-Neriah
Journal of Biological Chemistry 267 ( 7) 4518 -4523
95
1992
The inhibition of EGF-dependent proliferation of keratinocytes by tyrphostin tyrosine kinase blockers.
A Dvir , Y Milner , O Chomsky , C Gilon
Journal of Cell Biology 113 ( 4) 857 -865
76
1991