引用次数
引用: 62,626
H-指数: 82
I10-指数 : 135
出版物: 237
P53 is a direct regulator of the immune co-stimulatory molecule CD80
Baccarini A , Dhainaut M , Brown Bd , Rose S
bioRxiv
2021
Abstract PD03-05: A Novel Combination Therapy for Triple Negative Breast Cancer: Erlotinib and Metformin
YKI Lau , MM Pires , JM Shaw , JL Campbell
Cancer Research 70
2010
The molecular-basis of Turcot syndrome
SR Hamilton , B Liu , RE Parsons , NC Papadopolous
Gastroenterology 108 ( 4) A478 -A478
6
1995
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription
Nicole Steinbach , Dan Hasson , Deepti Mathur , Elias E Stratikopoulos
Nucleic Acids Research 47 ( 11) 5573 -5586
19
2019
Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant Cells
Xufen Yu , Jia Xu , Kaitlyn M Cahuzac , Ling Xie
Journal of Medicinal Chemistry 65 ( 20) 14237 -14260
2
2022
Design, synthesis, and evaluation of potent, selective, and bioavailable AKT kinase degraders
Xufen Yu , Jia Xu , Ling Xie , Li Wang
Journal of Medicinal Chemistry 64 ( 24) 18054 -18081
17
2021
151 Multimedia: a necessary step in the evolu-tion of research funding applications
Ashley E Webb , Anne Brunet , Michael TY Lam , Wenbo Li
SUPPLEMENTAL EXPERIMENTAL PROCEDURES
Bao-Liang Song , Navdar Sever , Russell A DeBose-Boyd
Inpatient administration of alpha-1-adrenergic receptor blocking agents reduces mortality in male COVID-19 patients
Shilong Li , Tomi Jun , Jonathan Tyler , Emilio Schadt
Frontiers in medicine 9 849222 -849222
3
2022
COVID-19 outcomes among hospitalized men with or without exposure to alpha-1-adrenergic receptor blocking agents (preprint)
Shilong Li , Tomi Jun , Zichen Wang , Yu-Han Kao
1
2021
A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma
Royce W Zhou , Jia Xu , Tiphaine C Martin , Alexis L Zachem
Nature Communications 13 ( 1) 6041 -6041
16
2022
A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma (vol 13, 6041, 2022)
Royce W Zhou , Jia Xu , Tiphaine C Martin , Alexis L Zachem
NATURE COMMUNICATIONS 14 ( 1)
2023
Author Correction: A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma
Royce W Zhou , Jia Xu , Tiphaine C Martin , Alexis L Zachem
nature communications 14
2023
AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
Kaitlyn M Cahuzac , Abigail Lubin , Kaitlyn Bosch , Nicole Stokes
Cell reports 42 ( 5)
11
2023
Discovery of potent, selective, and in vivo efficacious AKT kinase protein degraders via structure–activity relationship studies
Xufen Yu , Jia Xu , Yudao Shen , Kaitlyn M Cahuzac
Journal of medicinal chemistry 65 ( 4) 3644 -3666
27
2022
Serine threonine kinase (AKT) degradation/disruption compounds and methods of use
Jian Jin , Jing Liu , Ramon E Parsons , Jia Xu
6
2022
Molecular mechanisms in colitis-associated colorectal cancer
Royce W Zhou , Noam Harpaz , Steven H Itzkowitz , Ramon E Parsons
Oncogenesis 12 ( 1) 48 -48
5
2023
Etiology of super-enhancer reprogramming and activation in cancer
Royce W Zhou , Ramon E Parsons
Epigenetics & Chromatin 16 ( 1) 29 -29
4
2023
B7‐H3 drives immunosuppression and Co‐targeting with CD47 is a new therapeutic strategy in β‐catenin activated melanomas
Min Hsu , Tiphaine C Martin , Nikki S Vyas , Garrett Desman
Pigment Cell & Melanoma Research 36 ( 5) 407 -415
3
2023
SERINE THREONINE KINASE (AKT) DEGRADATION/INTERRUPTION COMPOUNDS AND METHODS OF USE
Jian Jin , Jing Liu , Ramon E Parsons , Jia Xu
1
2022