Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy

Nicolas Place , Martin Wohlwend , Johan Auwerx , Pénélope A. Andreux
Science Translational Medicine 13 ( 588)

47
2021
Impact of the Natural Compound Urolithin A on Health, Disease, and Aging.

Johan Auwerx , Pénélope A. Andreux , Pamela Valdés , Chris Rinsch
Trends in Molecular Medicine

80
2021
Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth

Laura Di Magno , Daniela Manzi , Davide D’Amico , Sonia Coni
Cell Cycle 13 ( 21) 3404 -3413

28
2014
Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth

Davide D’Amico , Laura Antonucci , Laura Di Magno , Sonia Coni
Developmental Cell 35 ( 1) 21 -35

68
2015
The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Davide D’Amico , Adrienne Mottis , Francesca Potenza , Vincenzo Sorrentino
Molecular Cell 73 ( 4) 775 -787.e10

80
2019
Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

Vincenzo Sorrentino , Mario Romani , Laurent Mouchiroud , John S. Beck
Nature 552 ( 7684) 187 -193

215
2017
Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons.

Lu Zheng , Nathalie Bernard-Marissal , Norman Moullan , Davide D’Amico
Human Molecular Genetics 26 ( 3) 582 -598

66
2017
Translating Hedgehog in Cancer: Controlling Protein Synthesis

Davide D’Amico , Gianluca Canettieri
Trends in Molecular Medicine 22 ( 10) 851 -862

9
2016
The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint

Laura Di Magno , Alessio Basile , Sonia Coni , Simona Manni
Oncotarget 7 ( 8) 9538 -9549

27
2016
Cytosolic Proteostasis Networks of the Mitochondrial Stress Response

Davide D’Amico , Vincenzo Sorrentino , Johan Auwerx
Trends in Biochemical Sciences 42 ( 9) 712 -725

55
2017
Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

Pedro M. Quirós , Miguel A. Prado , Nicola Zamboni , Davide D’Amico
Journal of Cell Biology 216 ( 7) 2027 -2045

524
2017
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults

Anurag Singh , Davide D’Amico , Penelope A Andreux , Andreane M Fouassier
Cell Reports Medicine 3 ( 5)

21
2022
Tetracycline-induced mitohormesis mediates disease tolerance against influenza

Adrienne Mottis , Terytty Y Li , Gaby El Alam , Alexis Rapin
The Journal of Clinical Investigation 132 ( 17)

2
2022
Effect of urolithin A supplementation on muscle endurance and mitochondrial health in older adults: a randomized clinical trial

Sophia Liu , Davide D’Amico , Eric Shankland , Saakshi Bhayana
JAMA network open 5 ( 1) e2144279 -e2144279

28
2022
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia

Pirkka-Pekka Laurila , Martin Wohlwend , Tanes Imamura de Lima , Peiling Luan
Nature Aging 2 ( 12) 1159 -1175

2
2022
Mitophagy in human health, ageing and disease

Anna Picca , Julie Faitg , Johan Auwerx , Luigi Ferrucci
Nature Metabolism 5 ( 12) 2047 -2061

19
2023
Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population

Anurag Singh , Davide D’Amico , Pénélope A Andreux , Gillian Dunngalvin
European Journal of Clinical Nutrition 1 -12

60
2021
Mitophagy Activation by Urolithin A to Target Muscle Aging

Julie Faitg , Davide D’Amico , Chris Rinsch , Anurag Singh
Calcified Tissue International 1 -7

2
2023
T3 preserves ovarian granulosa cells from chemotherapy-induced apoptosis

Cecilia Verga Falzacappa , Eleonora Timperi , Barbara Bucci , Donatella Amendola
Journal of Endocrinology 215 ( 2) 281 -289

24
2012
CNBP regulates wing development in Drosophila melanogaster by promoting IRES-dependent translation of dMyc

Laura Antonucci , Davide D'Amico , Laura Di Magno , Sonia Coni
Cell Cycle 13 ( 3) 434 -439

14
2014