Capillary electrophoresis reveals polyamine metabolism modulation in Leishmania (Leishmania) amazonensis wild-type and arginase-knockout mutants under arginine starvation

Emerson A. Castilho-Martins , Gisele A. B. Canuto , Sandra Marcia Muxel , Maria Fernanda Laranjeira daSilva
Electrophoresis 36 ( 18) 2314 -2323

15
2015
Arginine and Polyamines Fate in Leishmania Infection

Sandra M. Muxel , Juliana I. Aoki , Juliane C. R. Fernandes , Maria F. Laranjeira-Silva
Frontiers in Microbiology 8 2682

75
2018
The RelA/cRel nuclear factor-κB (NF-κB) dimer, crucial for inflammation resolution, mediates the transcription of the key enzyme in melatonin synthesis in RAW 264.7 macrophages.

Sandra Marcia Muxel , Maria Fernanda Laranjeira‐Silva , Claudia Emanuelle Carvalho‐Sousa , Lucile Maria Floeter‐Winter
Journal of Pineal Research 60 ( 4) 394 -404

31
2016
Melatonin attenuates Leishmania (L.) amazonensis infection by modulating arginine metabolism

Maria Fernanda Laranjeira‐Silva , Ricardo A Zampieri , Sandra M Muxel , Lucile Maria Floeter‐Winter
Journal of Pineal Research 59 ( 4) 478 -487

33
2015
Axenic Leishmania amazonensis Promastigotes Sense

EA Castilho-Martins , MF Laranjeira da Silva , MG dos Santos , SM Muxel

2011
Production of an antibody against L.(L.) amazonensis arginase

MF Laranjeira da Silva , IC Alves , K Framesqui , Lucile Maria Floeter-Winter
Revista do Instituto de Medicina Tropical de São Paulo 45 90 res. BC15 -90 res. BC15

2003
Biochemical and biophysical properties of a highly active recombinant arginase from Leishmania (Leishmania) amazonensis and possible sites for specific inhibition

Lucile Maria Floeter-Winter , Maria Fernanda Laranjeira Silva , Edson Roberto da Silva , Renato Arruda Mortara
Abstract

2009
One Health Approach to Leishmaniases: Understanding the Disease Dynamics through Diagnostic Tools.

Ahyun Hong , Ricardo Andrade Zampieri , Jeffrey Jon Shaw , Lucile Maria Floeter-Winter
Pathogenetics 9 ( 10) 809

3
2020
Leishmania (Leishmania ) amazonensis induces macrophage miR-294 and miR-721 expression and modulates infection by targeting NOS2 and L-arginine metabolism

Sandra Marcia Muxel , Maria Fernanda Laranjeira-Silva , Ricardo Andrade Zampieri , Lucile Maria Floeter-Winter
Scientific Reports 7 ( 1) 44141 -44141

46
2017
Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis.

Stephanie Maia Acuña , Juliana Ide Aoki , Maria Fernanda Laranjeira-Silva , Ricardo Andrade Zampieri
PLOS ONE 12 ( 11) 1 -21

24
2017
RNA-seq transcriptional profiling of Leishmania amazonensis reveals an arginase-dependent gene expression regulation.

Juliana Ide Aoki , Sandra Marcia Muxel , Ricardo Andrade Zampieri , Maria Fernanda Laranjeira-Silva
PLOS Neglected Tropical Diseases 11 ( 10) 1 -22

24
2017
Dual transcriptome analysis reveals differential gene expression modulation influenced by Leishmania arginase and host genetic background.

Juliana Ide Aoki , Sandra Marcia Muxel , Maria Fernanda Laranjeira-Silva , Ricardo Andrade Zampieri
Microbial genomics 6 ( 9)

5
2020
In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice.

Juliana Ide Aoki , Ahyun Hong , Ricardo Andrade Zampieri , Lucile Maria Floeter-Winter
Journal of Visualized Experiments ( 156)

2020
A Trypanosomatid Iron Transporter that Regulates Mitochondrial Function Is Required for Leishmania amazonensis Virulence

Bidyottam Mittra , Maria Fernanda Laranjeira-Silva , Juliana Perrone Bezerra de Menezes , Jennifer Jensen
PLOS Pathogens 12 ( 1) e1005340

30
2016
Quantification of Intracellular Growth Inside Macrophages is a Fast and Reliable Method for Assessing the Virulence of Leishmania Parasites.

Amrita Sarkar , Yousuf A. Khan , Maria Fernanda Laranjeira-Silva , Norma W. Andrews
Journal of Visualized Experiments ( 133) 57486

2
2018
Functional validation of miRNA-mRNA interactions in macrophages by inhibition/competition assays based in transient transfection

Sandra Marcia Muxel , Sandra Marcia Muxel , Maria Fernanda Laranjeira-Silva , Ricardo Andrade Zampieri
Protocol exchange

2
2017
The iron-dependent mitochondrial superoxide dismutase SODA promotes Leishmania virulence.

Bidyottam Mittra , Maria Fernanda Laranjeira-Silva , Danilo Ciccone Miguel , Juliana Perrone Bezerra de Menezes
Journal of Biological Chemistry 292 ( 29) 12324 -12338

33
2017
A MFS-like plasma membrane transporter required for Leishmania virulence protects the parasites from iron toxicity

Maria Fernanda Laranjeira-Silva , Wanpeng Wang , Tamika K. Samuel , Fernando Y. Maeda
PLOS Pathogens 14 ( 6)

9
2018
Leishmania infection inhibits macrophage motility by altering F-actin dynamics and the expression of adhesion complex proteins.

Juliana Perrone Bezerra de Menezes , Amrita Koushik , Satarupa Das , Can Guven
Cellular Microbiology 19 ( 3)

5
2017
Ascorbate-Dependent Peroxidase (APX) from Leishmania amazonensis Is a Reactive Oxygen Species-Induced Essential Enzyme That Regulates Virulence.

Lucia Xiang , Maria Fernanda Laranjeira-Silva , Fernando Y. Maeda , Jason Hauzel
Infection and Immunity 87 ( 12)

1
2019