gianluca selvaggio
机构: Fondazione The Microsoft Research - University of Trento Centre for Computational and System Biology
每年引用次数
引用次数
引用: 342
H-指数: 7
I10-指数 : 7
出版物: 34
INTEGRATION BETWEEN SIGNALING AND ANTIOXIDANT PROTECTION BY THE PEROXIREDOXIN/THIOREDOXIN/THIOREDOXIN-REDUCTASE SYSTEM
Gianluca Selvaggio , Armindo Salvador , Pedro M. B. M. Coelho
european conference on mathematical and theoretical biology
2014
In Silico Logical Modelling to Uncover Cooperative Interactions in Cancer.
Gianluca Selvaggio , Claudine Chaouiya , Florence Janody ,
International Journal of Molecular Sciences 22 ( 9) 4897
2021
Probing cellular arrhythmogenesis using the O’Hara-Rudy model of the undiseased human ventricular cardiomyocyte
Gianluca Selvaggio , Wan Hongbin , Robert A. Pearlstein
bioRxiv
2020
Hydrogen peroxide metabolism and sensing in human erythrocytes: A validated kinetic model and reappraisal of the role of peroxiredoxin II
Rui Benfeitas , Gianluca Selvaggio , Fernando Antunes , Pedro M.B.M. Coelho
Free Radical Biology and Medicine 74 35 -49
44
2014
Synthetic mixed-signal computation in living cells
Jacob R. Rubens , Gianluca Selvaggio , Timothy K. Lu
Nature Communications 7 ( 1) 11658 -11658
60
2016
Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia.
Hongbin Wan , Gianluca Selvaggio , Robert A. Pearlstein
PLOS ONE 15 ( 11)
4
2020
Hybrid epithelial-mesenchymal phenotypes are controlled by microenvironmental factors
Gianluca Selvaggio , Sara Canato , Archana Pawar , Pedro T. Monteiro
Cancer Research 80 ( 11) 2407 -2420
8
2020
Is Peroxiredoxin II’s peroxidase activity strongly inhibited in human erythrocytes?
Rui Benfeitas , Gianluca Selvaggio , Fernando Antunes , Pedro Coelho
Free Radical Biology and Medicine 75 S23 -S24
2014
Is the Peroxiredoxin 2/Thioredoxin/Thioredoxin Reductase system in human erythrocytes designed for redox signaling?
Rui Benfeitas , Gianluca Selvaggio , Fernando Antunes , Pedro Coelho
Free Radical Biology and Medicine 75 S24
1
2014
Integration between anticipatory blocking and redox signaling by the peroxiredoxin/thioredoxin/thioredoxin-reductase system
Gianluca Selvaggio , Pedro M.B.M. Coelho , Armindo Salvador
Free Radical Biology and Medicine 75 S47 -S48
1
2014
Biodynamics: A novel quasi-first principles theory on the fundamental mechanisms of cellular function/dysfunction and the pharmacological modulation thereof.
Gianluca Selvaggio , Robert Alan Pearlstein
PLOS ONE 13 ( 11)
8
2018
Exploring alternative quorum sensing model structures and quorum quenching strategies
Chiara Cimolato , Massimo Bellato , Gianluca Selvaggio , Luca Marchetti
bioRxiv 2023.07. 07.548074 -2023.07. 07.548074
2023
Literature mining and mechanistic graphical modelling to improve mRNA vaccine platforms
Lorena Leonardelli , Giuseppe Lofano , Gianluca Selvaggio , Silvia Parolo
Frontiers in Immunology 3655 -3655
5
A novel logical model of COVID-19 intracellular infection to support therapies development
Elena Piretto , Gianluca Selvaggio , Damiano Bragantini , Enrico Domenici
PLoS computational biology 18 ( 8) e1010443 -e1010443
2022
Use of quantitative systems pharmacology pipelines to bridge in vitro and in vivo results in drug discovery
Federico Reali , Attila Csikász-Nagy , Gianluca Selvaggio
Frontiers in Systems Biology 3 1291610 -1291610
2023
Uncovering quorum sensing and quenching structural properties: a systems biology approach
Chiara Cimolato , Gianluca Selvaggio , Massimo Bellato , Luca Marchetti
Pàtron Editore
2023
Shifting the paradigm from in vitro potency to non-equilibrium time-dependent drug-target occupancy under in vivo-relevant conditions
Robert Pearlstein , Daniel Mckay , Gianluca Selvaggio , Andrei Golosov
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254
2017
Computational Analysis of Cytokine Release Following Bispecific T-Cell Engager Therapy: Applications of a Logic-Based Model
Gianluca Selvaggio , Silvia Parolo , Pranami Bora , Lorena Leonardelli
Frontiers in Oncology 12 818641 -818641
6
2022
Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin–thioredoxin system. 1. Understanding commonalities and differences among cell types
Gianluca Selvaggio , Pedro MBM Coelho , Armindo Salvador
Redox Biology
32
2017
DESIGN SPACE ANALYSIS SUPPORTS ROLE OF PEROXIREDOXIN/THIOREDOXIN/THIOREDOXIN-REDUCTASE SYSTEM IN INTEGRATING REDOX SIGNALING AND ANTICIPATORY BLOCKING
Gianluca Selvaggio , Pedro MBM Coelho , Armindo Salvador
The 11th International Workshop on Computational Systems Biology, WCSB 2014, May 15-16, Lisbon, Portugal 22 -22