Christoph Sachse
机构: Innovation Campus Berlin, Nuvisan Pharma Services
每年引用次数
引用次数
引用: 5,921
H-指数: 25
I10-指数 : 28
出版物: 67
Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer.
Faye Turner , Gillian Smith , Christoph Sachse , Tracy Lightfoot
International Journal of Cancer 112 ( 2) 259 -264
65
2004
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures.
Dirk Schumacher , Geoffroy Andrieux , Karsten Boehnke , Marlen Keil
PLOS Genetics 15 ( 3)
24
2019
Oncology studies using siRNA libraries: the dawn of RNAi-based genomics.
Christoph Sachse , Christophe J Echeverri
Oncogene 23 ( 51) 8384 -8391
45
2004
miR-196 is an essential early-stage regulator of tail regeneration, upstream of key spinal cord patterning events
Tina Sehm , Christoph Sachse , Corina Frenzel , Karen Echeverri
Developmental Biology 334 ( 2) 468 -480
76
2009
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies.
Ralf Kittler , Vineeth Surendranath , Anne-Kristin Heninger , Mikolaj Slabicki
Nature Methods 4 ( 4) 337 -344
224
2007
Long-term therapeutic drug monitoring of clozapine and metabolites in psychiatric in- and outpatients
Michael Dettling , Christoph Sachse , Jürgen Brockmöller , Jürgen Schley
Psychopharmacology 152 ( 1) 80 -86
38
2000
Multiclass cancer classification in fresh frozen and formalin-fixed paraffin-embedded tissue by DigiWest multiplex protein analysis.
Teresa Bockmayr , Gerrit Erdmann , Denise Treue , Philipp Jurmeister
Laboratory Investigation 100 ( 10) 1288 -1299
5
2020
High-throughput RNA interference strategies for target discovery and validation by using synthetic short interfering RNAs: functional genomics investigations of biological pathways.
Christoph Sachse , Eberhard Krausz , Andrea Krönke , Michael Hannus
Methods in Enzymology 392 242 -277
38
2005
Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism.
Christoph Sachse , Upinder Bhambra , Gillian Smith , Tracy J. Lightfoot
British Journal of Clinical Pharmacology 55 ( 1) 68 -76
161
2003
Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine
Christoph Sachse , Jürgen Brockmöller , Steffen Bauer , Ivar Roots
British Journal of Clinical Pharmacology 47 ( 4) 445 -449
887
1999
Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin
Sükrü Aynacioglu , Jürgen Brockmöller , Steffen Bauer , Christoph Sachse
British Journal of Clinical Pharmacology 48 ( 3) 409 -415
221
1999
Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation
Katherine J. Aitchison , Janet Munro , Padraig Wright , Shulabade Smith
British Journal of Clinical Pharmacology 48 ( 3) 388 -394
36
1999
CYP2D6 genotyping as an alternative to phenotyping for determination of metabolic status in a clinical trial setting.
Suzin McElroy , Jodi Richmond , Maruja Lira , David Friedman
Aaps Pharmsci 2 ( 4) 1 -11
90
2000
Regenerative potential of adipocytes in hypertrophic scars is mediated by myofibroblast reprogramming
Katharina Hoerst , Lenie van den Broek , Christoph Sachse , Oliver Klein
Journal of Molecular Medicine 97 ( 6) 761 -775
9
2019
A rare insertion of T226 in exon 1 of CYP2D6 causes a frameshift and is associated with the poor metabolizer phenotype: CYP2D6*15.
Christoph Sachse , Jurgen Brockmoller , Steffen Bauer , Torsten Reum
Pharmacogenetics 6 ( 3) 269 -272
20
1996
Correctness of prediction of the CYP2D6 phenotype confirmed by genotyping 47 intermediate and poor metabolizers of debrisoquine.
Christoph Sachse , J??rgen Brockm??ller , Michael Hildebrand , Katrin M??ller
Pharmacogenetics 8 ( 2) 181 -185
60
1998
Detection of the GSTM1*0 allele by long polymerase chain reaction.
Reinhold Kerb , J??rgen Brockm??ller , Christoph Sachse , Ivar Roots
Pharmacogenetics 9 ( 1) 89 -94
24
1999
Evaluation of activity and combination strategies with the microtubule-targeting drug sagopilone in breast cancer cell lines.
Julia Eschenbrenner , Sebastian Winsel , Stefanie Hammer , Anette Sommer
Frontiers in Oncology 1 44 -44
7
2011
19-P002 miR-196 is an essential early-stage regulator of tail regeneration, upstream of key spinal cord patterning events
Tina Sehm , Christoph Sachse , Corina Frenzel , Karen Echeverri
Mechanisms of Development 126 S291
1
2009
A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
Christoph Sachse , Gillian Smith , Murray JV Wilkie , Jennifer H Barrett
Carcinogenesis 23 ( 11) 1839 -1850
247
2002