CDK 4/6 Inhibitors Sensitize PIK3CA Mutant Breast Cancer to PI3K Inhibitors
Sadhna R. Vora , Dejan Juric , Nayoon Kim , Mari Mino-Kenudson
Cancer Cell 26 ( 1) 136 -149
265
2014
Dissection of the Interplay between Class I PI3Ks and Rac Signaling in Phagocytic Functions
Carlotta Costa , Giulia Germena , Emilio Hirsch
The Scientific World Journal 10 1826 -1839
16
2010
p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.
Chiara Ambrogio , Claudia Voena , Andrea D. Manazza , Roberto Piva
Blood 106 ( 12) 3907 -3916
70
2005
Phosphoinositide 3-kinase p110γ in immunity
Carlotta Costa , Erica L. Martin-Conte , Emilio Hirsch
IUBMB Life 63 ( 9) n/a -n/a
25
2011
Phosphoinositide 3-kinases as a common platform for multi-hormone signaling.
Emilio Hirsch , Carlotta Costa , Elisa Ciraolo
Journal of Endocrinology 194 ( 2) 243 -256
117
2007
CC-Chemokine Ligand 16 Induces a Novel Maturation Program in Human Immature Monocyte-Derived Dendritic Cells
Paola Cappello , Tiziana Fraone , Laura Barberis , Carlotta Costa
Journal of Immunology 177 ( 9) 6143 -6151
20
2006
The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions
Ornella Azzolino , Fiorella Altruda , V. Marco Ranieri , Emilio Hirsch
Blood 118 ( 4) 1099 -1108
38
2011
Taming the PI3K team to hold inflammation and cancer at bay.
Emilio Hirsch , Elisa Ciraolo , Alessandra Ghigo , Carlotta Costa
Pharmacology & Therapeutics 118 ( 2) 192 -205
68
2008
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition
Aaron N Hata , Matthew J Niederst , Hannah L Archibald , Maria Gomez-Caraballo
Nature Medicine 22 ( 3) 262 -269
480
2016
The Anaplastic Lymphoma Kinase Controls Cell Shape and Growth of Anaplastic Large Cell Lymphoma through Cdc42 Activation
Chiara Ambrogio , Claudia Voena , Andrea D. Manazza , Cinzia Martinengo
Cancer Research 68 ( 21) 8899 -8907
49
2008
PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function
Miriam Martini , Daniel Monteyne , Elisa De Luca , Giulia Germena
Developmental Cell 28 ( 6) 647 -658
122
2014
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
Kenneth N. Ross , Teresa Moran , Emily Howe , Linnea E. Fulton
Nature Communications 6 ( 1) 6377 -6377
504
2015
mTOR Inhibition Specifically Sensitizes Colorectal Cancers with KRAS or BRAF Mutations to BCL-2/BCL-XL Inhibition by Suppressing MCL-1
Anthony C Faber , Erin M Coffee , Carlotta Costa , Anahita Dastur
Cancer Discovery 4 ( 1) 42 -52
95
2014
EGF816 Exerts Anticancer Effects in Non–Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor
Yong Jia , Jose Juarez , Jie Li , Mari Manuia
Cancer Research 76 ( 6) 1591 -1602
79
2016
The double life of p85.
Carlotta Costa , Jeffrey A. Engelman
Cancer Cell 26 ( 4) 445 -447
11
2014
Measurement of PIP3 Levels Reveals an Unexpected Role for p110β in Early Adaptive Responses to p110α-Specific Inhibitors in Luminal Breast Cancer
Carlotta Costa , Hiromichi Ebi , Miriam Martini , Sean A Beausoleil
Cancer Cell 27 ( 1) 97 -108
128
2015
Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination
Jungoh Ham , Carlotta Costa , Renata Sano , Timothy L Lochmann
Cancer Cell 29 ( 2) 159 -172
62
2016
MEK Inhibition Leads to PI3K/AKT Activation by Relieving a Negative Feedback on ERBB Receptors
Alexa B. Turke , Youngchul Song , Carlotta Costa , Rebecca Cook
Cancer Research 72 ( 13) 3228 -3237
218
2012
Leukocyte transmigration is modulated by chemokine‐mediated PI3Kγ‐dependent phosphorylation of vimentin
Laura Barberis , Christian Pasquali , Dominique Bertschy-Meier , Alessandra Cuccurullo
European Journal of Immunology 39 ( 4) 1136 -1146
50
2009
Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer
Anthony C Faber , Anna F Farago , Carlotta Costa , Anahita Dastur
Proceedings of the National Academy of Sciences of the United States of America 112 ( 11) 201411848
126
2015