Jiekun Xuan, Ph.D.
机构: U.S. Food and Drug Administration
每年引用次数
引用次数
引用: 3,004
H-指数: 24
I10-指数 : 29
出版物: 39
Novel deletion mutation of DSRAD in a Chinese family with Dyschromatosis Symmetrica Hereditaria (DSH).
Anli Shu , Guang He , Xingwang Li , Junwei Meng
European Journal of Dermatology 17 ( 3) 247 -248
5
2007
Screening for SNPs and haplotypes in the CYP3A7 gene in Chinese populations.
Jing Du , Yongyong Shi , Aiping Zhang , Lei Wang
Pharmacogenomics 8 ( 6) 559 -566
5
2007
HLA-A*02:01 allele is associated with tanshinone-induced cutaneous drug reactions in Chinese population.
Qinyuan Zhu , Yanzhou Zhang , Jiekun Xuan , Fanping Yang
Pharmacogenomics Journal 20 ( 3) 408 -414
2020
The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.
Qiangen Wu , Baitang Ning , Jiekun Xuan , Zhen Ren
Toxicology Letters 253 55 -62
22
2016
Next-generation sequencing in the clinic: promises and challenges.
Jiekun Xuan , Ying Yu , Tao Qing , Lei Guo
Cancer Letters 340 ( 2) 284 -295
360
2013
Sertraline induces endoplasmic reticulum stress in hepatic cells.
Si Chen , Jiekun Xuan , Letha Couch , Advait Iyer
Toxicology 322 78 -88
40
2014
Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells.
Zhen Ren , Si Chen , Tao Qing , Jiekun Xuan
Toxicology 392 11 -21
30
2017
Mitochondrial dysfunction induced by leflunomide and its active metabolite.
Jiekun Xuan , Zhen Ren , Tao Qing , Letha Couch
Toxicology 33 -45
40
2018
A pharmacogenetic study of risperidone on histamine H3 receptor gene (HRH3) in Chinese Han schizophrenia patients.
Zhiyun Wei , Lei Wang , Mengmeng Zhang , Jiekun Xuan
Journal of Psychopharmacology 26 ( 6) 813 -818
16
2012
Comparison of RNA-seq and microarray-based models for clinical endpoint prediction
Wenqian Zhang , Ying Yu , Falk Hertwig , Jean Thierry-Mieg
Genome Biology 16 ( 1) 133 -133
330
2015
Dual indexed design of in-Drop single-cell RNA-seq libraries improves sequencing quality and throughput
Austin N. Southard Smith , Alan J. Simmons , Bob Chen , Angela L. Jones
bioRxiv 835488
2019
Sertraline, an Antidepressant, Induces Apoptosis in Hepatic Cells Through the Mitogen-Activated Protein Kinase Pathway
Si Chen , Jiekun Xuan , Liqing Wan , Haixia Lin
Toxicological Sciences 137 ( 2) 404 -415
64
2014
Effects of the dopamine D3 receptor (DRD3) gene polymorphisms on risperidone response: a pharmacogenetic study.
Jiekun Xuan , Xinzhi Zhao , Guang He , Lan Yu
Neuropsychopharmacology 33 ( 2) 305 -311
33
2008
Pharacogenetic effects of dopamine transporter gene polymorphisms on response to chlorpromazine and clozapine and on extrapyramidal syndrome in schizophrenia
Mingqing Xu , Qinghe Xing , Sheng Li , Yonglan Zheng
Progress in Neuro-Psychopharmacology and Biological Psychiatry 34 ( 6) 1026 -1032
36
2010
Association analysis of serotonin receptor 7 gene (HTR7) and risperidone response in Chinese schizophrenia patients.
Zhiyun Wei , Lei Wang , Jiekun Xuan , Ronglin Che
Progress in Neuro-psychopharmacology & Biological Psychiatry 33 ( 3) 547 -551
23
2009
A case-control association study between the CYP3A4 and CYP3A5 genes and schizophrenia in the Chinese Han population.
Jing Du , Yifeng Xu , Shiwei Duan , Aiping Zhang
Progress in Neuro-psychopharmacology & Biological Psychiatry 33 ( 7) 1200 -1204
10
2009
Ginkgo biloba leaf extract induces DNA damage by inhibiting topoisomerase II activity in human hepatic cells
Zhuhong Zhang , Si Chen , Hu Mei , Jiekun Xuan
Scientific Reports 5 ( 1) 14633 -14633
56
2015
microRNAs in Drug-Induced Liver Toxicity
Jiekun Xuan , Lei Guo ,
microRNAs in Toxicology and Medicine 33 -47
2
2013
microRNA Profiling: Strategies and Challenges
Jiekun Xuan , Leming Shi , Lei Guo
microRNAs in Toxicology and Medicine 437 -455
1
2013
Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity.
Jiekun Xuan , Si Chen , Baitang Ning , William H. Tolleson
Chemico-Biological Interactions 255 63 -73
73
2016