Benzoxadiazole Derivatives: Atypical Inhibitors ofAldose Reductase

Taliani , Cosconati , Novellino , Pietra La
XXIV Congresso Nazionale della Società Chimica Italiana

2011
Multi-target agents for the treatment of type II diabetic disorder: the new challenge in pharmacotherapy

Da Settimo F , La Motta C , M Morelli , S Sartini
Transworld Research Network 193 -216

2010
NOVEL KINASE INHIBITORS IN THYROID CANCER TREATMENT: SYNTHESIS AND BIOLOGICAL EVALUATION

Guido Bocci , Concettina La Motta , S Sartini , Sabrina Taliani
NUOVE PROSPETTIVE IN CHIMICA FARMACEUTICA 6°

2012
Aldose reductase inhibition: a new strategy to control the enzyme activity in hyperglycemic conditions

Francesco Balestri , Concettina La Motta , S Sartini , Mario Cappiello
56th national meeting of the italian society of biochemistry and molecular biology 219 -219

2012
A novel bioisoster of flavonoids attenuates cytokine-induced endothelial dysfunction and promotes cell proliferation

S Del Turco , C Saponaro , B Dario , S Sartini
CARDIOVASCULAR RESEARCH 93 S77 -S77

2012
S. salerno, AM Marini, FD Settimo, A. Lavecchia, E. Novellino, M. Cartore, P. Failli and M. Ciuffi

CL Motta , S Sartini , L Mugnaini , F Simorini
J. Med. Chem 50 4917 -4927

5
2007
Inhibition of ocular aldose reductase by a new benzofuroxane derivative ameliorates rat endotoxic uveitis.

Clara Di Filippo , MV Zippo , R Maisto , MC Trotta
Mediators of Inflammation 2014 857958 -857958

9
2014
Derivati a nucleo benzo[d]isotiazol-3(2H)-one-1,1-diossido e loro impiego nel trattamento di tumori

Guido Bocci , Concettina La Motta , Stefania Sartini , Vito Coviello

2014
Derivati a nucleo pirazolo[3,4-d]pirimidinico quali inibitori di proteine tirosina chinasi

M Del Tacca , Guido Bocci , Concettina La Motta , Stefania Sartini

1
2007
Functional Studies in the Year of Pulses: the case of Zolfino landraces (Phaesolus vulgaris L.)

Alessandra Braca , Francesco Balestri , Carlo Sorce , Concettina La Motta
XI Congresso Italiano di Chimica degli Alimenti

2016
Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells

Guido Bocci , Anna Fioravanti , Concettina La Motta , Paola Orlandi
Biochemical Pharmacology 81 ( 11) 1309 -1316

19
2011
Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors.

Sara Consalvi , Salvatore Alfonso , Angela Di Capua , Giovanna Poce
Bioorganic & Medicinal Chemistry 23 ( 4) 810 -820

14
2015
Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic complications

Umberto Mura , Sandro Cosconati , Luciana Marinelli , Ettore Novellino
European Journal of Medicinal Chemistry 46 ( 7) 2797 -2806

64
2011
CLM29, a multi-target pyrazolopyrimidine derivative, has anti-neoplastic activity in medullary thyroid cancer in vitro and in vivo.

Alessandro Antonelli , Guido Bocci , Concettina La Motta , Silvia Martina Ferrari
Molecular and Cellular Endocrinology 393 ( 1) 56 -64

14
2014
Novel Pyrazolopyrimidine Derivatives as Tyrosine Kinase Inhibitors with Antitumoral Activity in Vitro and in Vivo in Papillary Dedifferentiated Thyroid Cancer

Alessandro Antonelli , Guido Bocci , Concettina La Motta , Silvia Martina Ferrari
The Journal of Clinical Endocrinology and Metabolism 96 ( 2) 195 -195

61
2011