Novel Thiazole Carboxylic Acid Derivatives Possessing a “Zinc Binding Feature” as Potential Human Glyoxalase-I Inhibitors

Qosay A. Al-Balasa , Mohammad A. Hassana , Ghazi A. Al Jabala , Nizar A. Al-Shar
Letters in Drug Design & Discovery 14 ( 11) 1324 -1334

14
2017
Enhanced Antimicrobial Activity of AamAP1-Lysine, a Novel Synthetic Peptide Analog Derived from the Scorpion Venom Peptide AamAP1.

Ammar Almaaytah , Shadi Tarazi , Ahmad Abu-Alhaijaa , Yara Altall
Pharmaceuticals 7 ( 5) 502 -516

17
2014
Recent Advances in Glyoxalase-I Inhibition.

Qosay A. Al-Balas , Mohammad A. Hassan , Nizar A. Al-Shar'i , Ghazi A. Al Jabal
Mini-reviews in Medicinal Chemistry 19 ( 4) 281 -291

18
2019
Design, synthesis and biological evaluation of novel glyoxalase I inhibitors possessing diazenylbenzenesulfonamide moiety as potential anticancer agents.

Buthina A. Al-Oudat , Hana'a M. Jaradat , Qosay A. Al‑Balas , Nizar A. Al-Shar'i
Bioorganic & Medicinal Chemistry 28 ( 16) 115608

2020
Molecular Dynamics Simulations of Adenosine Receptors: Advances, Applications and Trends

Nizar A. Al-Shar'i , Qosay A. Al-Balas
Current Pharmaceutical Design 25 ( 7) 783 -816

22
2019
Synthesis and anticandidal activity of azole-containing sulfonamides.

Amjad M. Qandil , Mohammad A. Hassan , Nizar A. Al-Shar'i
Archiv Der Pharmazie 341 ( 2) 99 -112

8
2008
Computational and experimental exploration of the structure-activity relationships of flavonoids as potent glyoxalase-I inhibitors.

Qosay A. Al-Balas , Mohammad A. Hassan , Nizar A. Al-Shar'i , Tamam El-Elimat
Drug Development Research 79 ( 2) 58 -69

12
2018
Design, Synthesis and Biological Evaluation of Potential Novel Zinc Binders Targeting Human Glyoxalase-I; A Validated Target for Cancer Treatment

Nizar Al-Shar'i , Ammar Almaaytah , Qosay Ali Al-Balas , Mohammad Hassan
Jordan Journal of Pharmaceutical Sciences 11 ( 1)

1
2018
Enhancement of levodopa stability when complexed with β-cyclodextrin in transdermal patches.

Rana Obaidat , Nizar Al-Shar'i , Bassam Tashtoush , Tamara Athamneh
Pharmaceutical Development and Technology 23 ( 10) 986 -997

6
2018
Computer-aided technologies in drug discovery and toxicity prediction

Bhakti Pawar , Santosh Kumar Behera , Muktika Tekade , Nizar Al-Shar'i
Academic Press 239 -254

2023
Identification of CHK1 Kinase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking

N. A. Al-Shar I , Sondos Musleh
Indian Journal of Pharmaceutical Sciences 82 ( 3) 472 -482

1
2020
Hit identification of SMYD3 enzyme inhibitors using structure-based pharmacophore modeling.

Soraya M Alnabulsi , Nizar A Al-shar’i
Future Medicinal Chemistry 11 ( 10) 1107 -1117

1
2019
Evaluation of EDTA dianhydride versus diphenyl carbonate nanosponges for curcumin

Hadeia Mashaqbeh , Rana Obaidat , Nizar A Al-shar’i
AAPS PharmSciTech 23 ( 7) 229 -229

4
2022
Novel glyoxalase-I inhibitors possessing a “zinc-binding feature” as potential anticancer agents

Qosay Al-Balas , Mohammad Hassan , Nizar Alshari , Nizar Mhaidat
Drug Design Development and Therapy 10 2623 -2629

24
2016
The Design and Functional Characterization of the Antimicrobial and Antibiofilm Activities of BMAP27-Melittin, a Rationally Designed Hybrid Peptide

Ammar Almaaytah , Shadi Tarazi , Mohammad Al-Fandi , Ahmad Abuilhaija
International Journal of Peptide Research and Therapeutics 21 ( 2) 165 -177

6
2015
In Vitro Synergistic Activities of the Hybrid Antimicrobial Peptide MelitAP-27 in Combination with Conventional Antibiotics Against Planktonic and Biofilm Forming Bacteria

Ammar Almaaytah , Adan Alnaamneh , Ahmad Abualhaijaa , Nizar Alshari’
International Journal of Peptide Research and Therapeutics 22 ( 4) 497 -504

1
2016
The impact of cycleanine in cancer research: a computational study

Ogochukwu Ngozi Nwaefulu , Nizar A Al-Shar’i , Josephine Omonkhelin Owolabi , Sreenivasa Rao Sagineedu
Journal of Molecular Modeling 28 ( 11) 340

2022
Antitubercular, cytotoxicity, and computational target validation of dihydroquinazolinone derivatives

Katharigatta N Venugopala , Nizar A Al-Shar’i , Lina A Dahabiyeh , Wafa Hourani
Antibiotics 11 ( 7) 831

4
2022