Using our mini-brains: cerebral organoids as an improved cellular model for human prion disease.
CathrynL Haigh , BradleyR Groveman , Ryan Walters
Neural Regeneration Research 15 ( 6) 1019 -1020
2
2020
RT-QuIC of olfactory neuroepithelium brushings as a definitive intravital test for sporadic Creutzfeldt-Jakob disease diagnosis
Christina Doriana Orru , M. Bongianni , S. Monaco , M. Fiorini
Prion
2013
Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cells.
J. A. Carroll , B. R. Groveman , K. Williams , R. Moore
Scientific Reports 10 ( 1) 6654
2
2020
Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt-Jakob disease.
Bradley Groveman , Natalia C. Ferreira , Simote Foliak , Ryan O. Walters
Scientific Reports 11 ( 1) 5165 -5165
1
2021
The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases
Matthias Schmitz , Maria Cramm , Franc Llorens , Dominik Müller-Cramm
Nature Protocols 11 ( 11) 2233 -2242
66
2016
Hereditary E200K mutation within the prion protein gene alters human iPSC derived cardiomyocyte function
Aleksandar R Wood , Simote T Foliaki , Bradley R Groveman , Ryan O Walters
Scientific Reports 12 ( 1) 15788
1
2022
Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction
Simote T Foliaki , Anna Smith , Benjamin Schwarz , Eric Bohrnsen
PLoS Genetics 19 ( 1) e1010565
2023
Correction to: Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC
Bradley R Groveman , Christina D Orrù , Andrew G Hughson , Lynne D Raymond
Acta Neuropathologica Communications 8 1 -2
4
2020
Sporadic Creutzfeldt–Jakob disease infected human cerebral organoids retain the original human brain subtype features following transmission to humanized transgenic mice
Bradley R Groveman , Brent Race , Simote T Foliaki , Katie Williams
Acta Neuropathologica Communications 11 ( 1) 28 -28
3
2023
Detection and diagnosis of prion diseases using RT-QuIC: an update
Byron Caughey , Christina D Orru , Bradley R Groveman , Matilde Bongianni
Prion Diseases 173 -181
3
2017
How to perform olfactory mucosa brushing in patients with Creutzfeldt-Jakob disease
Christina D Orru , Matilde Bongianni , Giovanni Tonoli , Andrew G Hughson
PRION 8 22 -23
1
2014
Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces
Christina D Orrú , Bradley R Groveman , Andrew G Hughson , Tomás Barrio
PLoS Pathogens 20 ( 4) e1012175 -e1012175
2024
Rapid and ultra-sensitive quantitation of disease-associated alpha-synuclein seeds in brain and cerebrospinal fluid by alpha Syn RT-QuIC (vol 6, 7, 2018)
Bradley R Groveman , Christina D Orru , Andrew G Hughson , Lynne D Raymond
ACTA NEUROPATHOLOGICA COMMUNICATIONS 8 ( 1)
2020
Diagnosis and biomarkers of Parkinson's and Dementia with Lewy bodies: rapid and ultra-sensitive quantitation of disease-associated alpha-synuclein by alpha Syn RT-QuIC
Christina D Orru , Bradley R Groveman , Andrew G Hughson , Lynne D Raymond
PRION 13 65 -66
2019
Human cerebral organoids propagate sporadic CJD prions
Bradley R Groveman , Simote Foliaki , Christina D Orru , Gianluigi Zanusso
PRION 13 74 -74
2019
An improved test for the detection of Creutzfeldt-Jakob Disease from human CSF using new RT-QuIC conditions
Bradley R Groveman , Christina D Orru , Andrew G Hughson , Gianluigi Zanusso
PRION 9 S23 -S23
2015
Comparison of brushes and swabs for olfactory mucosa sampling and RT-QuIC analysis of patients with Creutzfeldt-Jakob disease
Matilde Bongianni , Christina D Orru , Giovanni Tonoli , Andrew G Hughson
PRION 8 118 -118
2014
Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease
Tze How Mok , Akin Nihat , Nour Majbour , Danielle Sequeira
Brain 146 ( 6) 2570 -2583
12
2023
Trajectories of neurodegeneration and seed amplification biomarkers prior to disease onset in individuals at risk of prion disease
Tze How Mok , Akin Nihat , Nour Majbour , Danielle Sequeira
medRxiv 2022.10. 30.22281644 -2022.10. 30.22281644
1
2022
Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease
Sara Hall , Christina D Orrù , Geidy E Serrano , Douglas Galasko
Acta neuropathologica communications 10 ( 1) 90 -90
39
2022