BPN14770 Alleviates Cognitive Impairment and Amyloid Pathology in APP/PS1/hPDE4D Mice

Jinpeng Lyu , Ying Xu , Shichao Gao , Mark Gurney
NEUROPSYCHOPHARMACOLOGY 45 ( SUPPL 1) 330 -330

2020
BPN14770 Clinical Development for Fragile X Syndrome

Mark Gurney , Michael Tranfaglia , Patrica Cogram , Scott Reines
NEUROTHERAPEUTICS 15 ( 3) 827 -827

2018
Structural biology and molecular pharmacology of phosphodiesterase 4 (PDE4) regulation

Mark Gurney
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248

2014
Biaryl substituted heterocycle inhibitors of lta4h for treating inflammation

Jasbir Singh , Vincent Sandanayaka , Mark Gurney , Peng Yu

2014
2009
PVASP as a biomarker for platelet activation: Inhibition of the EP3 receptor by the novel antiplatelet agent DG-041 prevents pVASP dephosphorylation

Maria Bjarnadottir , Olafur Magnusson , Adalheidur G Hansdottir , Gudrun V Halldorsdottir
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 28 ( 6) E103 -E103

2008
DG-051: A novel leukotriene A4 hydrolase inhibitor for the treatment of myocardial infarction and stroke

Jasbir Singh , Vincent Sandanayaka , Bjorn Mamat , Jennifer Winger
DRUGS OF THE FUTURE 32 26 -26

2007
Reduction of plaque size and 5LO, AL0X5P, and LTA4H gene expression a dyslipidemic mouse model of atherogenesis by DG-031, an inhibitor of leukotriene biosynthesis

Jon Mar Bjornsson , Einar Jorundsson , Gudmundur Sigthorsson , Thorkell Andresson
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 27 ( 6) E60 -E60

2007
DG-041, a novel antiplatelet agent, is a potent and selective antagonist of the EP3 receptor for prostaglandin E2

Jasbir Singh , Thorkell Andresson , Jose Ramirez , Wayne Zeller
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 27 ( 6) E80 -E80

2007
The EP3 receptor for prostaglandin E2 in peripheral arterial disease

Maria Bjarnadottir , Thorkell Andresson , Kolbeinn Gudmundsson , Mark Gurney
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 27 ( 6) E109 -E109

2007
Biaryl substituted heterocycle inhibitors of lta4h for treating inflammation

Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat

2007
MEDI 420-Design, synthesis, and SAR of novel leukotriene A4 hydrolase inhibitors containing chiral piperidine and piperazine scaffolds

Vincent Sandanayaka , Bjorn Mamat , Louis Bedell , Nikhil Bhagat
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 232

2006
MEDI 419-Discovery of indazole derivatives as potent leukotriene A4 hydrolase inhibitors

Lei Zhao , Bjorn Mamat , Rama Mishra , Guorun Halldorsdottir
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 232

2006
ORCA–Online Research@ Cardiff

Magdalena A Czubala , Robert H Jenkins , Mark Gurney , Leah Wallace