A non-canonical role for glutamate decarboxylase 1 in cancer cell amino acid homeostasis, independent of the GABA shunt.
E. Loginicheva , J. Blagih , T. Griss , N. Jones
bioRxiv
2021
LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis
M. C. Poffenberger , A. Metcalfe-Roach , E. Aguilar , J. Chen
Science 361 ( 6400) 406 -411
13
2018
TORC)ing up purine biosynthesis
E. H. Ma , R. G. Jones
Science 351 ( 6274) 670 -671
6
2016
Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function.
Maria L Balmer , Eric H Ma , Glenn R Bantug , Jasmin Grählert
Immunity 44 ( 6) 1312 -1324
141
2016
The miR-17∼92 microRNA Cluster Is a Global Regulator of Tumor Metabolism
Said Izreig , Bozena Samborska , Radia M. Johnson , Alexey Sergushichev
Cell Reports 16 ( 7) 1915 -1928
39
2016
Immunometabolism in the Tumor Microenvironment
Dominic G. Roy , Irem Kaymak , Kelsey S. Williams , Eric H. Ma
Annual Review of Cancer Biology 5 ( 1) 137 -159
1
2021
Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells.
Eric H. Ma , Mark J. Verway , Radia M. Johnson , Dominic G. Roy
Immunity 51 ( 5) 856
212
2019
Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration
Hannah Guak , Sara Al Habyan , Eric H. Ma , Haya Aldossary
Nature Communications 9 ( 1) 2463
60
2018
Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.
Dominic G. Roy , Jocelyn Chen , Victoria Mamane , Eric H. Ma
Cell Metabolism 31 ( 2) 250 -266
145
2020
Memory CD8+ T Cells Balance Pro- and Anti-inflammatory Activity by Reprogramming Cellular Acetate Handling at Sites of Infection.
Maria L. Balmer , Eric H. Ma , Andrew J. Thompson , Raja Epple
Cell Metabolism 32 ( 3)
7
2020
Serine Is an Essential Metabolite for Effector T Cell Expansion
Eric H Ma , Glenn Bantug , Takla Griss , Stephanie Condotta
Cell Metabolism 25 ( 2) 345 -357
224
2017
Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation.
Brenda Raud , Dominic G. Roy , Ajit S. Divakaruni , Tatyana N. Tarasenko
Cell Metabolism 28 ( 3) 504
252
2018
Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
Laura Hulea , Simon-Pierre Gravel , Masahiro Morita , Marie Cargnello
Cell Metabolism 28 ( 6) 817
29
2018
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.
Anne-Valérie Burgener , Glenn R. Bantug , Benedikt J. Meyer , Rebecca Higgins
Nature Immunology 20 ( 10) 1311 -1321
11
2019
Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis
Takla Griss , Emma E. Vincent , Robert Egnatchik , Jocelyn Chen
PLOS Biology 13 ( 12) e1002309
126
2015
AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species.
Rebecca C. Rabinovitch , Bozena Samborska , Brandon Faubert , Eric H. Ma
Cell Reports 21 ( 1) 1 -9
374
2017
Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis
Brian E. Hsu , Sébastien Tabariès , Radia M. Johnson , Sylvia Andrzejewski
Cell Reports 27 ( 13) 3902
44
2019
The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance.
Leeanna El-Houjeiri , Elite Possik , Tarika Vijayaraghavan , Mathieu Paquette
Cell Reports 26 ( 13) 3613
41
2019
Mitochondrial cyclophilin D regulates T cell metabolic responses and disease tolerance to tuberculosis.
Fanny Tzelepis , Julianna Blagih , Nargis Khan , Joshua Gillard
Science immunology 3 ( 23)
36
2018
Methotrexate elicits pro-respiratory and anti-growth effects by promoting AMPK signaling.
David J. Papadopoli , Eric H. Ma , Dominic Roy , Mariana Russo
Scientific Reports 10 ( 1) 7838
4
2020