Simon-Pierre Gravel
机构: Professeur agrégé / Associate professor - Faculté de pharmacie, Université de Montréal
主页: umontreal.ca
每年引用次数
引用次数
引用: 3,905
H-指数: 22
I10-指数 : 25
出版物: 44
LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis
M. C. Poffenberger , A. Metcalfe-Roach , E. Aguilar , J. Chen
Science 361 ( 6400) 406 -411
13
2018
A cullin‐based ubiquitin ligase is involved in virus‐mediated IRF3 degradation
Annie Bibeau‐Poirier , Genevieve Rodier , Philippe Coulombe , Simon‐Pierre Gravel
The FASEB Journal 20 ( 5) A1352 -A1352
2006
The proinflammatory actions of angiotensin II are mediated through the phosphorylation of p65/Rel A on Ser 536
Douillette Annie , Bibeau‐Poirier Annie , Gravel Simon‐Pierre , Servant Marc
The FASEB Journal 20 ( 4) A532 -A532
2006
Activation of interferon regulatory factor 3 in human cytomegalovirus-infected vascular smooth muscle cells, a possible link in pathogen-induced atherosclerosis development
SP Gravel , M Servant
Biochemistry and Cell Biology 82 ( 6) 764 -764
2004
AMPK maintains cellular metabolic homeostasis through regulation of mitochondrial reactive oxygen species. Cell Rep. 2017; 21 (1): 1-9
RC Rabinovitch , B Samborska , B Faubert , EH Ma
dx. doi. org/10.1016/j. celrep 26
34
2017
Metformin directly acts on mitochondria to alter cellular bioenergetics. Cancer Metab. 2014; 2: 12
S Andrzejewski , SP Gravel , M Pollak , J St-Pierre
Epub 2014/09/04. doi: 10.1186/2049-3002-2-12. PubMed PMID: 25184038
19
Rôles des kinases IKK et IKK-related dans les maladies inflammatoires chroniques : implications dans l’athérosclérose et la réponse hypoxique
Simon-Pierre Gravel
2011
185 IKK-related kinases are repressors of HIF-1 transcriptional activity
Simon-Pierre Gravel , Darren E. Richard , Marc J. Servant
Cytokine 43 ( 3) 283 -283
2008
Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation
Annie Bibeau-Poirier , Simon-Pierre Gravel , Jean-François Clément , Sébastien Rolland
Journal of Immunology 177 ( 8) 5059 -5067
71
2006
mTOR coordinates protein synthesis, mitochondrial activity and proliferation.
Masahiro Morita , Simon-Pierre Gravel , Laura Hulea , Ola Larsson
Cell Cycle 14 ( 4) 473 -480
437
2015
Roles of an IκB Kinase-related Pathway in Human Cytomegalovirus-infected Vascular Smooth Muscle Cells A MOLECULAR LINK IN PATHOGEN-INDUCED PROATHEROSCLEROTIC CONDITIONS
Simon-Pierre Gravel , Marc J. Servant
Journal of Biological Chemistry 280 ( 9) 7477 -7486
32
2005
mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation
Masahiro Morita , Simon-Pierre Gravel , Valérie Chénard , Kristina Sikström
Cell Metabolism 18 ( 5) 698 -711
699
2013
Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
Laura Hulea , Simon-Pierre Gravel , Masahiro Morita , Marie Cargnello
Cell Metabolism 28 ( 6) 817
29
2018
Immunometabolic modulation of retinal inflammation by CD36 ligand
Katia Mellal , Samy Omri , Mukandila Mulumba , Houda Tahiri
Scientific Reports 9 ( 1) 12903
7
2019
The Proinflammatory Actions of Angiotensin II Are Dependent on p65 Phosphorylation by the IκB Kinase Complex
Annie Douillette , Annie Bibeau-Poirier , Simon-Pierre Gravel , Jean-François Clément
Journal of Biological Chemistry 281 ( 19) 13275 -13284
61
2006
RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.
Thibault Houles , Simon-Pierre Gravel , Geneviève Lavoie , Sejeong Shin
Cancer Research 78 ( 9) 2191 -2204
19
2018
Interplay between ShcA Signaling and PGC-1α Triggers Targetable Metabolic Vulnerabilities in Breast Cancer.
Young Kyuen Im , Ouafa Najyb , Simon-Pierre Gravel , Shawn McGuirk
Cancer Research 78 ( 17) 4826 -4838
6
2018
Alternative polyadenylation confers Pten mRNAs stability and resistance to microRNAs.
Caroline Thivierge , Hsin-Wei Tseng , Vinay K Mayya , Carine Lussier
Nucleic Acids Research 46 ( 19) 10340 -10352
27
2018
Translational and HIF1α-dependent metabolic reprograming underpin oncometabolome plasticity and synergy between oncogenic kinase inhibitors and biguanides.
Laura Hulea , Simon-Pierre Gravel , Masahiro Morita , Marie Cargnello
bioRxiv 160879
2017
Metformin directly acts on mitochondria to alter cellular bioenergetics
Sylvia Andrzejewski , Simon-Pierre Gravel , Michael Pollak , Julie St-Pierre
Cancer and Metabolism 2 ( 1) 12 -12
240
2014
Michael Pollak ivan topisirovic Daina Avizonis Masahiro Morita Ola Larsson Sylvia Andrzejewski Arnim Pause, M.Sc., Ph.D. Valentina Gandin Laura Hulea Tommy Alain Chadi Zakaria Russell G Jones Nahum Sonenberg Vincent Giguere Brandon Faubert Marie Cargnello Eric H Ma Sylvain Meloche Shawn McGuirk Genevieve Deblois