The malignancy of metastatic ovarian cancer cells is increased on soft matrices through a mechanosensitive Rho–ROCK pathway
D. J. McGrail , Q. M. N. Kieu , M. R. Dawson
Journal of Cell Science 127 ( 12) 2621 -2626
62
2014
Osmotic Regulation Is Required for Cancer Cell Survival under Solid Stress
Daniel J. McGrail , Kathleen M. McAndrews , Chandler P. Brandenburg , Nithin Ravikumar
Biophysical Journal 109 ( 7) 1334 -1337
45
2015
Validation of cancer-type-dependent benefit from immune checkpoint blockade in TMB-H tumors identified by the FoundationOne CDx assay
DJ McGrail , PG Pilié , NU Rashid , L Voorwerk
Annals of Oncology 33 ( 11) 1204 -1206
2
2022
Reply to:‘Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab.’by D. Fabrizio et al.
DJ McGrail , PG Pilié , NU Rashid , L Voorwerk
Annals of Oncology 32 ( 9) 1194 -1197
2
2021
Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer
L Federico , DJ McGrail , S-E Bentebibel , C Haymaker
Annals of Oncology 33 ( 1) 42 -56
25
2022
High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types.
DJ McGrail , PG Pilié , NU Rashid , L Voorwerk
Annals of Oncology 32 ( 5) 661 -672
416
2021
Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm. NPJ Syst Biol Appl. 2017; 3: 8
DJ McGrail , CC Lin , J Garnett , Q Liu
DOI: https://doi. org/10.1038/s41540-017-0011-6 8 -8
6
A murine preclinical syngeneic transplantation model for breast cancer precision medicine
Lorenzo Federico , Zechen Chong , Dong Zhang , Daniel J McGrail
Sci Adv 19 ( 3(4))
14
2017
CHD4 mutations promote endometrial cancer stemness by activating TGF-beta signaling
Hui Dai , Kaiyi Li , Yang Li , Daniel J McGrail
American Journal of Cancer Research 8 ( 5) 903 -914
6
2018
Nucleostemin Modulates Outcomes of Hepatocellular Carcinoma via a Tumor Adaptive Mechanism to Genomic Stress
Junying Wang , Daniel J McGrail , Parnit K Bhupal , Wen Zhang
Molecular Cancer Research 18 ( 5) 723 -734
2020
e-MutPath: computational modeling reveals the functional landscape of genetic mutations rewiring interactome networks.
Yongsheng Li , Brandon Burgman , Ishaani S Khatri , Sairahul R Pentaparthi
Nucleic Acids Research 49 ( 1)
2021
Spatially coordinated changes in intracellular rheology and extracellular force exertion during mesenchymal stem cell differentiation
Kathleen M McAndrews , Daniel J McGrail , Nhat D Quach , Michelle R Dawson
Physical Biology 11 ( 5) 056004 -056004
8
2014
Actomyosin tension as a determinant of metastatic cancer mechanical tropism.
Daniel J McGrail , Quang Minh N Kieu , Jason A Iandoli , Michelle R Dawson
Physical Biology 12 ( 2) 026001
19
2015
Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non--Small-Cell Lung Cancer Data Set
Stephanie T Schmidt , Neal Akhave , Ryan E Knightly , Alexandre Reuben
JCO Clinical Cancer Informatics 6 e2200040
2022
Immune checkpoint blockade in glioblastoma: from tumor heterogeneity to personalized treatment
Víctor A Arrieta , Crismita Dmello , Daniel J McGrail , Daniel J Brat
The Journal of Clinical Investigation 133 ( 2)
2023
PD-L1 sustains chronic, cancer cell--intrinsic responses to type I interferon, enhancing resistance to DNA damage
HyeonJoo Cheon , Elise G Holvey-Bates , Daniel J McGrail , George R Stark
Proceedings of the National Academy of Sciences 118 ( 47) e2112258118
14
2021
Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers
Daniel J McGrail , Patrick G Pilié , Hui Dai , Truong Nguyen Anh Lam
Science translational medicine 13 ( 617) eabe6201
13
2021
Defining the condensate landscape of fusion oncoproteins
Swarnendu Tripathi , Hazheen K Shirnekhi , Scott D Gorman , Bappaditya Chandra
Nature communications 14 ( 1) 6008 -6008
14
2023
Multiomics analyses reveal DARS1-AS1/YBX1–controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance
Caishang Zheng , Yanjun Wei , Qiang Zhang , Ming Sun
Science advances 9 ( 31) eadf3984 -eadf3984
22
2023
Biomolecular condensation: a new phase in cancer research
Anupam K Chakravarty , Daniel J McGrail , Thomas M Lozanoski , Brandon S Dunn
Cancer discovery 12 ( 9) 2031 -2043
7
2022