R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis.
Daniel Braas , Lai N. Chan , Lai N. Chan , David R. Plas
Molecular Cell 81 ( 5)
115
2021
The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia.
Chao Shen , Ming-Tai Chen , Xin-Hua Zhang , Xiao-Lin Yin
PLOS Genetics 12 ( 9)
29
2016
Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC.
Chenying Li , Lei Dong , Rui Su , Ying Bi
Haematologica 105 ( 1) 148 -160
34
2020
MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia
Xiao-Shuang Wang , Jia-Nan Gong , Jia Yu , Fang Wang
Blood 119 ( 21) 4992 -5004
141
2012
c-Myc suppresses miR-451⊣YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia
Rui Su , Jia-Nan Gong , Ming-Tai Chen , Li Song
Oncotarget 7 ( 47) 77430 -77443
18
2016
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
Rui Su , Lei Dong , Yangchan Li , Min Gao
Cancer Cell 38 ( 1)
288
2020
microRNA-451-modulated hnRNP A1 takes a part in granulocytic differentiation regulation and acute myeloid leukemia.
Li Song , Hai-Shuang Lin , Jia-Nan Gong , Hua Han
Oncotarget 8 ( 33) 55453 -55466
6
2017
ZFP36L1 promotes monocyte/macrophage differentiation by repressing CDK6.
Ming-Tai Chen , Lei Dong , Xin-Hua Zhang , Xiao-Lin Yin
Scientific Reports 5 ( 1) 16229 -16229
27
2015
Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia.
Xi Jiang , Chao Hu , Kyle Ferchen , Ji Nie
Nature Communications 8 ( 1) 2099
45
2017
miR-199a-5p inhibits monocyte/macrophage differentiation by targeting the activin A type 1B receptor gene and finally reducing C/EBPα expression
Hai-Shuang Lin , Jia-Nan Gong , Rui Su , Ming-Tai Chen
Journal of Leukocyte Biology 96 ( 6) 1023 -1035
29
2014
PU.1-Regulated Long Noncoding RNA lnc-MC Controls Human Monocyte/Macrophage Differentiation through Interaction with MicroRNA 199a-5p.
Ming-Tai Chen , Hai-Shuang Lin , Chao Shen , Yan-Ni Ma
Molecular and Cellular Biology 35 ( 18) 3212 -3224
54
2015
Histone H3 trimethylation at lysine 36 guides m 6 A RNA modification co-transcriptionally
Huilin Huang , Hengyou Weng , Keren Zhou , Tong Wu
Nature 567 ( 7748) 414 -419
354
2019
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification
Hengyou Weng , Huilin Huang , Huizhe Wu , Xi Qin
Cell Stem Cell 22 ( 2) 191 -205
670
2017
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
Chao Shen , Yue Sheng , Allen C. Zhu , Sean Robinson
Cell Stem Cell 27 ( 1)
181
2020
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
Rui Su , Lei Dong , Yangchan Li , Min Gao
Nature cell biology 24 ( 2) 205 -216
53
2022
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
Li Han , Lei Dong , Keith Leung , Zhicong Zhao
Cell Stem Cell 30 ( 1) 52 -68
1
2023
RBFOX2 recognizes N 6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation
Xiaoyang Dou , Yu Xiao , Chao Shen , Kitty Wang
Nature cell biology 25 ( 9) 1359 -1368
13
2023
Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia
Zhenhua Chen , Keren Zhou , Jianhuang Xue , Andrew Small
Science translational medicine 15 ( 689) eabq8513 -eabq8513
4
2023
RNA m6A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression
Zheng Zhang , Keren Zhou , Li Han , Andrew Small
Genes & Diseases 11 ( 1) 382 -396
9
2024
DNA N6-methyldeoxyadenosine in mammals and human disease
Chao Shen , Kitty Wang , Xiaolan Deng , Jianjun Chen
Trends in Genetics 38 ( 5) 454 -467
25
2022