Pradeepkumar PI
机构: Professor of Chemistry, IIT Bombay
每年引用次数
引用次数
引用: 2,492
H-指数: 25
I10-指数 : 42
出版物: 77
The 3′-modified antisense oligos promote faster hydrolysis of the target RNA by RNase H than the natural counterpart
Edouard Zamaratski , Dimitri Ossipov , P.I Pradeepkumar , Nariman Amirkhanov
Tetrahedron 57 ( 3) 593 -606
16
2001
Transmission of the conformational information in the antisense:RNA hybrid duplex influences the pattern of the RNase H cleavage reaction †
P.I Pradeepkumar , E Zamaratski , A Földesi , J Chattopadhyaya
Tetrahedron Letters 41 ( 44) 8601 -8607
28
2000
Dihydrochelerythrine and its derivatives: Synthesis and their application as potential G-quadruplex DNA stabilizing agents
Rajesh Malhotra , Chhanda Rarhi , K.V. Diveshkumar , Rajib Barik
Bioorganic & Medicinal Chemistry 24 ( 13) 2887 -2896
9
2016
Cationic red emitting fluorophore: A light up NIR fluorescent probe for G4-DNA
Beena Kumari , Akanksha Yadav , Sushree P. Pany , P.I. Pradeepkumar
Journal of Photochemistry and Photobiology B: Biology 190 128 -136
5
2019
A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H.
Edouard Zamaratski , P.I. Pradeepkumar , Jyoti Chattopadhyaya
Journal of Biochemical and Biophysical Methods 48 ( 3) 189 -208
178
2001
Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to both exo and endonucleases
Pushpangadan. I. Pradeepkumar , Nariman V. Amirkhanov , Jyoti Chattopadhyaya
Organic and Biomolecular Chemistry 1 ( 1) 81 -92
47
2003
Nucleoside Analogues with a Seven-Membered Sugar Ring: Synthesis and Structural Compatibility in DNA--RNA Hybrids
Sunit Kumar Jana , S Harikrishna , Sruthi Sudhakar , Roberto El-Khoury
The Journal of Organic Chemistry 87 ( 5) 2367 -2379
1
2022
Translesion Synthesis across the N 2-Ethyl-deoxyguanosine Adduct by Human PrimPol
Elizaveta O Boldinova , Pratibha P Ghodke , Sruthi Sudhakar , Vipin Kumar Mishra
ACS Chemical Biology 17 ( 11) 3238 -3250
5
2022
info: doi/10.1002% 2F1521-3757% 2820020916% 29114% 3A18% 3C3552% 3A% 3AAID-ANGE3552% 3E3. 0. CO% 3B2-N 2021-06-30 JJ: 10.1002 J: 10.1002: 143 Angewandte ChemieAngew. Chem. 004482491521375711418Elizabeth M. BoonJacqueline K. BartonPushpangadan I. PradeepkumarJohanIsakssonCatherinePetitJyotiChattopadhyaya916200235523555 http://doi. wiley. com/10.1002/tdm_license_1. 1 10.1002/1521-3757 (20020916) 114: 18< 3552:: AID-ANGE3552> 3.0. CO; 2-Nhttps://onlinelibrary. wiley. com
Elizabeth M Boon , Jacqueline K Barton , Pushpangadan I Pradeepkumar , Johan Isaksson
Angewandte Chemie 114 ( 18) 3552 -3555
2002
Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to both exo and endonucleasesElectronic supplementary information (ESI) available: RNA cleavage kinetics. See http: www. rsc. orgsuppdataobb2b210163g
Pushpangadan Pradeepkumar , Nariman V Amirkhanov , Jyoti Chattopadhyaya
2003
RNA-Cleaving DNA Enzymes and Their Potential Therapeutic Applications as Antibacterial and Antiviral Agents
P. I. Pradeepkumar , Claudia Höbartner
From Nucleic Acids Sequences to Molecular Medicine 371 -410
2
2012
Probing the Binding Interactions between Chemically Modified siRNAs and Human Argonaute 2 Using Microsecond Molecular Dynamics Simulations
S. Harikrishna , P. I. Pradeepkumar
Journal of Chemical Information and Modeling 57 ( 4) 883 -896
8
2017
Specific Recognition of Promoter G-Quadruplex DNAs by Small Molecule Ligands and Light-up Probes
V. Dhamodharan , P. I. Pradeepkumar
ACS Chemical Biology 14 ( 10) 2102 -2114
46
2019
Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn2+-dependent deoxyribozymes that use 2′,3′-cyclic phosphate RNA substrates
Diana M. Kost , Joseph P. Gerdt , P. I. Pradeepkumar , Scott K. Silverman
Organic and Biomolecular Chemistry 6 ( 23) 4391 -4398
14
2008
Fluorescence Quenching Studies of γ-Butyrolactone Binding Protein (CprB) from Streptomyces coelicolor A3(2)
Anwesha Biswas , Ravi K. Swarnkar , Bhukya Hussain , Suraj K. Sahoo
Journal of Physical Chemistry B 118 ( 34) 10035 -10042
15
2014
Site-selective depurination by a periodate-dependent deoxyribozyme.
Claudia Höbartner , P. I. Pradeepkumar , Scott K. Silverman
Chemical Communications ( 22) 2255 -2257
25
2007
Investigating Pharmacological Targeting of G-Quadruplexes in the Human Malaria Parasite.
Mohammad Anas , Richa Sharma , V Dhamodharan , PI Pradeepkumar
Biochemistry 56 ( 51) 6691 -6699
6
2017
Synthesis and Polymerase-Mediated Bypass Studies of the N2-Deoxyguanosine DNA Damage Caused by a Lucidin Analogue
Pratibha P. Ghodke , S. Harikrishna , P. I. Pradeepkumar
Journal of Organic Chemistry 80 ( 4) 2128 -2138
6
2015
Influence of 2'-fluoro versus 2'-O-methyl substituent on the sugar puckering of 4'-C-aminomethyluridine.
Kiran R. Gore , S. Harikrishna , P. I. Pradeepkumar
Journal of Organic Chemistry 78 ( 19) 9956 -9962
16
2013
Incorporation of 4'-C-aminomethyl-2'-O-methylthymidine into DNA by thermophilic DNA polymerases.
Ganesh N. Nawale , Kiran R. Gore , Claudia Höbartner , P. I. Pradeepkumar
Chemical Communications 48 ( 77) 9619 -9621
7
2012