Edward Manser
机构: Senior Principal Investigator, IMCB
每年引用次数
引用次数
引用: 18,043
H-指数: 62
I10-指数 : 103
出版物: 144
The GTPase-deficient Rnd Proteins Are Stabilized by Their Effectors
Liuh Ling Goh , Ed Manser
Journal of Biological Chemistry 287 ( 37) 31311 -31320
22
2012
Small GTPases Take the Stage
Ed Manser
Developmental Cell 3 ( 3) 323 -328
28
2002
Why an A-loop phospho-mimetic fails to activate PAK1: understanding an inaccessible kinase state by molecular dynamics simulations.
Yuen-Wai Ng , Devanathan Raghunathan , Perry M. Chan , Yohendran Baskaran
Structure 18 ( 7) 879 -890
26
2010
NMR binding and crystal structure reveal that intrinsically-unstructured regulatory domain auto-inhibits PAK4 by a mechanism different from that of PAK1
Wei Wang , Liangzhong Lim , Yohendran Baskaran , Ed Manser
Biochemical and Biophysical Research Communications 438 ( 1) 169 -174
18
2013
Signaling via a novel integral plasma membrane pool of a serine/threonine protein kinase PRK1 in mammalian cells
Simon C. Watkins , Bee Jen Tan , Robert Z. Qi , Ed Manser
The FASEB Journal 18 ( 14) 1722 -1724
22
2004
The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.
Widyawilis Selamat , Pei-Ling Felicia Tay , Yohendran Baskaran , Ed Manser
PLOS ONE 10 ( 6)
23
2015
βPak-interacting Exchange Factor-mediated Rac1 Activation Requires smgGDS Guanine Nucleotide Exchange Factor in Basic Fibroblast Growth Factor-induced Neurite Outgrowth
Eun-Young Shin , Chan-Soo Lee , Tae Goo Cho , Young Gyu Kim
Journal of Biological Chemistry 281 ( 47) 35954 -35964
25
2006
Collapsin Response Mediator Proteins (CRMPs) Are a New Class of Microtubule-associated Protein (MAP) That Selectively Interacts with Assembled Microtubules via a Taxol-sensitive Binding Interaction
Pao-Chun Lin , Perry M. Chan , Christine Hall , Ed Manser
Journal of Biological Chemistry 286 ( 48) 41466 -41478
67
2011
A Functional Requirement for PAK1 Binding to the KH(2) Domain of the Fragile X Protein-Related FXR1
Evonne Say , Hwee-Goon Tay , Zhuo-shen Zhao , Yohendran Baskaran
Molecular Cell 38 ( 2) 236 -249
34
2010
PAK5 is auto-activated by a central domain that promotes kinase oligomerization
Bahareh Tabanifar , Zhuoshen Zhao , Ed Manser
Biochemical Journal 473 ( 12) 1777 -1789
5
2016
PAKs in human disease.
Perry M. Chan , Ed Manser
Progress in Molecular Biology and Translational Science 106 171 -187
28
2012
DAAM1 Is a Formin Required for Centrosome Re-Orientation during Cell Migration
Su-Fen Ang , Zhuo-shen Zhao , Louis Lim , Ed Manser
PLoS ONE 5 ( 9) e13064
51
2010
Regulation of IRSp53-Dependent Filopodial Dynamics by Antagonism between 14-3-3 Binding and SH3-Mediated Localization
Jeffrey M. Robens , Lee Yeow-Fong , Elsa Ng , Christine Hall
Molecular and Cellular Biology 30 ( 3) 829 -844
37
2010
Group I and II mammalian PAKs have different modes of activation by Cdc42
Yohendran Baskaran , Yuen‐Wai Ng , Widyawilis Selamat , Felicia Tay Pei Ling
EMBO Reports 13 ( 7) 653 -659
74
2012
Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network
Weiwei Luo , Zi Zhao Lieu , Ed Manser , Alexander D. Bershadsky
PLOS ONE 11 ( 10) e0163915 -22
15
2016
Cdc42-dependent nuclear translocation of non-receptor tyrosine kinase, ACK.
Ijaz Ahmed , Yolanda Calle , Mohammed A Sayed , Jabeen M Kamal
Biochemical and Biophysical Research Communications 314 ( 2) 571 -579
13
2004
PAK family kinases: Physiological roles and regulation.
Zhuo-shen Zhao , Ed Manser
Cellular logistics 2 ( 2) 59 -68
70
2012
The PAKs come of age: Celebrating 18 years of discovery.
Jeffrey Field , Ed Manser
Cellular logistics 2 ( 2) 54 -58
17
2012
The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation
Joseph E. Aslan , Sandra M. Baker , Cassandra P. Loren , Kristina M. Haley
American Journal of Physiology-cell Physiology 305 ( 5)
36
2013
A Robust Protocol to Map Binding Sites of the 14-3-3 Interactome: Cdc25C Requires Phosphorylation of Both S216 and S263 to bind 14-3-3
Perry M. Chan , Yuen-Wai Ng , Ed Manser
Molecular & Cellular Proteomics 10 ( 3)
14
2011