Ly6C+ Inflammatory Monocyte Differentiation Partially Mediates Hyperhomocysteinemia-Induced Vascular Dysfunction in Type 2 Diabetic db/db Mice
Pu Fang (方璞) , Xinyuan Li (李欣源) , Huimin Shan (单慧敏) , Jason J. Saredy
Arteriosclerosis, Thrombosis, and Vascular Biology 39 ( 10) 2097 -2119
19
2019
Metabolic reprogramming in resting and activated immune cells
H Sun , X Li
Metabolomics: open access 7 ( 1)
13
2017
IL-35 is a Novel Responsive Anti-inflammatory Cytokine - A New System of Categorizing Anti-inflammatory Cytokines
Xinyuan Li , Jietang Mai , Anthony Virtue , Ying Yin
The FASEB Journal 26
274
2012
Myeloid-Derived Suppressor Cell Differentiation in Cancer: Transcriptional Regulators and Enhanceosome-Mediated Mechanisms.
Youhai H. Chen , Xinyuan Li , Ting Li , Norman Fultang
Frontiers in Immunology 11 619253 -619253
2
2021
Mitochondrial ROS, uncoupled from ATP synthesis, determine endothelial activation for both physiological recruitment of patrolling cells and pathological recruitment of inflammatory cells.
Xinyuan Li , Pu Fang , William Y. Yang , Kylie Chan
Canadian Journal of Physiology and Pharmacology 95 ( 3) 247 -252
44
2017
c-Rel Is a Myeloid Checkpoint for Cancer Immunotherapy.
Ting Li , Xinyuan Li , Ali Zamani , Wei Wang
Nature Cancer 1 ( 5) 507 -517
15
2020
Lysophospholipids induce innate immune transdifferentiation of endothelial cells, resulting in prolonged endothelial activation
Xinyuan Li , Luqiao Wang , Pu Fang , Yu Sun
Journal of Biological Chemistry 293 ( 28) 11033 -11045
28
2018
TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling.
Jason R. Goldsmith , Nina Spitofsky , Ali Zamani , Ryan Hood
Nature Communications 11 ( 1) 2591
17
2020
Early Hyperlipidemia Promotes Endothelial Activation via a Caspase-1-Sirtuin 1 Pathway
Ying Yin , Xinyuan Li , Xiaojin Sha , Hang Xi
Arteriosclerosis, Thrombosis, and Vascular Biology 35 ( 4) 804 -816
159
2015
Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers
Xinyuan Li , Pu Fang , Jietang Mai , Eric T Choi
Journal of Hematology & Oncology 6 ( 1) 19 -19
767
2013
Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell Activation
Xinyuan Li , Pu Fang , Yafeng Li , Yin-Ming Kuo
Arteriosclerosis, Thrombosis, and Vascular Biology 36 ( 6) 1090 -1100
180
2016
IL-35 (Interleukin-35) Suppresses Endothelial Cell Activation by Inhibiting Mitochondrial Reactive Oxygen Species-Mediated Site-Specific Acetylation of H3K14 (Histone 3 Lysine 14)
Xinyuan Li , Ying Shao , Xiaojin Sha , Pu Fang
Arteriosclerosis, Thrombosis, and Vascular Biology 38 ( 3) 599 -609
37
2018
Identification of homocysteine-suppressive mitochondrial ETC complex genes and tissue expression profile - Novel hypothesis establishment.
Ramon Cueto , Lixiao Zhang , Hui Min Shan , Xiao Huang
Redox biology 17 70 -88
22
2018
Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells – Novel qualification markers for chronic disease risk factors and conditional DAMPs
Yifan Lu , Yu Sun , Charles Drummer , Gayani K. Nanayakkara
Redox biology 24 101221
21
2019
Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune memory signature in endothelial cells
Xinyuan Li , Pu Fang , Yu Sun , Ying Shao
Redox biology 28 101373
56
2020
Inhibition of Caspase-1 Activation in Endothelial Cells Improves Angiogenesis: A NOVEL THERAPEUTIC POTENTIAL FOR ISCHEMIA.
Jahaira Lopez-Pastrana , Lucas M. Ferrer , Ya-Feng Li , Xinyu Xiong
Journal of Biological Chemistry 290 ( 28) 17485 -17494
52
2015
Caspase-8 promotes c-Rel–dependent inflammatory cytokine expression and resistance against Toxoplasma gondii
Alexandra A. DeLaney , Corbett T. Berry , David A. Christian , Andrew Hart
Proceedings of the National Academy of Sciences of the United States of America 116 ( 24) 11926 -11935
14
2019
Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis.
Hangfei Fu , Yu Sun , Ying Shao , Jason Saredy
Frontiers in Immunology 11 595813 -595813
4
2020
Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages.
Zahidul Alam , Samir Devalaraja , Minghong Li , Tsun Ki Jerrick To
Cell Reports 31 ( 13) 107825
3
2020
Identification of novel pretranslational regulatory mechanisms for NF-κB activation.
Xiao Huang , Ren Gong , Xinyuan Li , Anthony Virtue
Journal of Biological Chemistry 288 ( 22) 15628 -15640
11
2013