Aldo-keto reductases and cancer drug resistance

Penning , Trevor M and Jonnalagadda , Sravan and Trippier , Paul C and Ri{\v{z
Pharmacological reviews 73 ( 3) 1150 -1171

35
2021
Synthetic routes to the oxazolomycin antibiotics.

M Moloney , P Trippier , P Bulger
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 224

2002
C; Yaqoob M; Wang Z Curr

MG Moloney , P Trippier
Drug Disc. Technol 1 ( 3) 181 -199

2
2004
Cancer Drug Resistance., 2021, 73

T Penning , S Jonnalagadda , P Trippier , TL Rižner Aldo-Keto Reductases
DOI: https://doi. org/10.1124/pharmrev 120 1150 -1171

2
Synthesis of highly substituted heterocycles

P Trippier , Paul Charles Trippier
University of Oxford

2006
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Trippier PC McGuigan C MedChemComm
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7
2010
Strategies, Synthesis, and Successes., 2020, 63

S Kumari , A Carmona , AK Tiwari , PC Trippier Amide Bond Bioisosteres
DOI: https://doi. org/10.1021/acs. jmedchem. 0c00530. PMID: https://www. ncbi. nlm. nih. gov/pubmed/32686940 12290 -12358

3
Development of A Novel RON Targeted Antibody‐Drug Conjugates using Cysteine Bridging Technology for Potential Treatment of Pancreatic Cancer

Sreedhar Reddy Suthe , Hang‐Ping Yao , paul c trippier , ming‐hai wang
The FASEB Journal 32 807.7 -807.7

2018
SERMACS-SWRM

Kshitij Verma , Paul Trippier12

Small molecule inhibitors for acute myeloid leukemia: where is the field heading?

Paul C Trippier
Future Medicinal Chemistry 9 ( 13) 1453 -1456

1
2017
Phenylboronic-acid-based carbohydrate binders as antiviral therapeutics: monophenylboronic acids

Paul C Trippier , Christopher McGuigan , Jan Balzarini
Antiviral Chemistry & Chemotherapy

2010
Back to the medicinal chemistry future

Mariateresa Giustiniano , Christian W Gruber , Caitlin N Kent , Paul C Trippier
Journal of Medicinal Chemistry 64 ( 21) 15515 -15518

1
2021
Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model

Krishnaiah Maddeboina , Sravan K Jonnalagadda , Ahmed Morsy , Ling Duan
Journal of Medicinal Chemistry 66 ( 14) 9894 -9915

1
2023
Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader

Angelica V Carmona , Shirisha Jonnalagadda , Alfie M Case , Krishnaiah Maddeboina
Communications Chemistry 7 ( 1) 95 -95

2024
Identification and characterization of two structurally related dipeptides that enhance catalytic efficiency of neurolysin

Srinidhi Jayaraman , Joanna Kocot , Shiva Hadi Esfahani , Naomi J Wangler
Journal of Pharmacology and Experimental Therapeutics 379 ( 2) 191 -202

8
2021
Functionalized Allopurinols targeting amyloid-binding alcohol dehydrogenase rescue Aβ-induced mitochondrial dysfunction

Ahmed Morsy , Krishnaiah Maddeboina , Ju Gao , Hezhen Wang
ACS Chemical Neuroscience 13 ( 14) 2176 -2190

10
2022
Excellence in Medicinal Chemistry: Celebrating ACS Medicinal Chemistry Division (MEDI) Awards. A Call for Nominations

Maria-Jesus Blanco , Amanda Bryant-Friedrich , Gunda Georg , Amjad Ali
Journal of medicinal chemistry 66 ( 11) 7067 -7069

2023
Evaluation of Urea-Based Inhibitors of the Dopamine Transporter Using the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

Md Ashraf-Uz-Zaman , Guangchen Ji , Dalton Tidwell , Linda Yin
ACS chemical neuroscience 13 ( 2) 217 -228

3
2022
Pivotal role of nitrogen heterocycles in Alzheimer’s disease drug discovery

Shikha Kumari , Krishnaiah Maddeboina , Rinda Devi Bachu , Sai HS Boddu
Drug Discovery Today 27 ( 10) 103322 -103322

23
2022