Defining the Lowest Threshold for Amyloid-PET to Predict Future Cognitive Decline and Amyloid Accumulation

Michelle E Farrell , Shu Jiang , Aaron P Schultz , Michael J Properzi
Neurology 96 ( 4)

4
2021
Lower novelty-related locus coeruleus function is associated with Aβ-related cognitive decline in clinically healthy individuals

Prokopis C Prokopiou , Nina Engels-Domínguez , Kathryn V Papp , Matthew R Scott
Nature Communications 13 ( 1) 1571 -1571

34
2022
Kinetic evaluation and assessment of longitudinal changes in reference region and extracerebral [18F] MK-6240 PET uptake

Jessie Fanglu Fu , Cristina Lois , Justin Sanchez , J Alex Becker
Journal of Cerebral Blood Flow & Metabolism 43 ( 4) 581 -594

8
2023
Association of pathologic and volumetric biomarker changes with cognitive decline in clinically normal adults: Harvard Aging Brain Study

Bernard J Hanseeuw , Heidi IL Jacobs , Aaron P Schultz , Rachel F Buckley
Neurology 101 ( 24) e2533 -e2544

2
2023
Longitudinal hippocampal atrophy is associated with cognitive decline independently of amyloid and tau in neocortex

Bernard Hanseeuw , Heidi IL Jacobs , Aaron P Schultz , Rachel F Buckley
Alzheimer's & Dementia 18 e069271 -e069271

2022
Association of emerging β-amyloid and tau pathology with early cognitive changes in clinically normal older adults

Michelle E Farrell , Kathryn V Papp , Rachel F Buckley , Heidi IL Jacobs
Neurology 98 ( 15) e1512 -e1524

23
2022
Optimizing early detection of beta‐amyloid accumulation with PET using spatial extent

Michelle E Farrell , Emma G Thibault , Alex Becker , Julie C Price
Alzheimer's & Dementia 18 e068029 -e068029

1
2022
AD‐causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains

Stephanie A Schultz , Ricardo Francisco Allegri , Aaron P Schultz , Alison Goate
Alzheimer's & Dementia 18 e067186 -e067186

1
2022
A longitudinal analysis of depressive symptoms in relation to repeated measurements of regional tau

Catherine E Munro , Rachel F Buckley , Patrizia Vannini , Bernard Hanseeuw
Alzheimer's & Dementia 18 e068136 -e068136

2022
Defining the ATN framework using longitudinal biomarker trajectories reveals an emerging amyloid accumulation group

Rory Thomas Boyle , Gillian T Coughlan , Michael J Properzi , Claire Archdeacon
Alzheimer's & Dementia 18 e068001 -e068001

2022
Developing early vulnerable area aggregates for PET detection of beta‐amyloid based on young and middle‐aged adults from the Framingham Heart Study

Emma G Thibault , Michelle E Farrell , Alexa S Beiser , Alex Becker
Alzheimer's & Dementia 18 e067870 -e067870

2022
Regional beta‐amyloid and tau deposition: Results from the Framingham Heart Study

Emma G Thibault , Michelle E Farrell , Alexa S Beiser , Justin S Sanchez
Alzheimer's & Dementia 17 e056508 -e056508

2021
Self‐reported history of estrogen hormone therapy differentiates rates of amyloid accumulation (PiB‐PET) relative to males: Findings from the Harvard Aging Brain Study

Zoe B Rubinstein , Rachel F Buckley , Matthew R Scott , Lyssa K Manning
Alzheimer's & Dementia 17 e056069 -e056069

2021
Sequential early cognitive changes sensitive to rising beta‐amyloid and tau pathology in preclinical AD

Michelle E Farrell , Kate V Papp , Rachel F Buckley , Heidi IL Jacobs
Alzheimer's & Dementia 17 e056315 -e056315

2021
Longitudinal associations between amyloid and tau‐PET: Impact for prevention trials

Bernard Hanseeuw , Heidi IL Jacobs , Alex Becker , Rachel F Buckley
Alzheimer's & Dementia 17 e056208 -e056208

2021
Multimodal neuroimaging biomarkers of Alzheimer’s disease in older adults with depression: Preliminary findings from a pilot cohort

Danielle V Mayblyum , Pranitha Y Premnath , Zoe B Rubinstein , Justin S Sanchez
Alzheimer's & Dementia 17 e057824 -e057824

2021
Estimating the Sequence of Change on Cognitive and Biomarker Trajectories in the Harvard Aging Brain Study

Hsiang-Chin Lori Chou , Aaron P Schultz , Heidi IL Jacobs , Kate V Papp
AAIC Neuroscience Next

2020
Surface-based amyloid and tau correlates of digital clock drawing performance

Danielle V Mayblyum , Justin S Sanchez , Emma G Thibault , Heidi IL Jacobs
2020 Alzheimer's Association International Conference

2020
Distinct contributions of longitudinal tau and amyloid to decline in various cognitive domains in preclinical AD

Michelle E Farrell , Kate V Papp , Heidi IL Jacobs , Rachel F Buckley
2020 Alzheimer's Association International Conference

2020
O1‐10‐03: ANATOMICAL STAGING OF BETA‐AMYLOID ACCUMULATION BASED ON LONGITUDINAL ASSESSMENT OF GLOBALLY PIB NEGATIVE ADULTS

Michelle E Farrell , Aaron P Schultz , Michael J Properzi , Heidi IL Jacobs
Alzheimer's & Dementia 15 P220 -P221

2019