引用次数
引用: 3,422
H-指数: 30
I10-指数 : 41
出版物: 124
Similarities between TNF and exogenous oxidants on the cytotoxic response of c-Myc-expressing fibroblasts in vitro.
Vuokko L Kinnula , Henrikka Aito , Juha Klefstrom , Kari Alitalo
Cancer Letters 125 ( 1) 191 -198
5
1998
c-Myc augments the apoptotic activity of cytosolic death receptor signaling proteins by engaging the mitochondrial apoptotic pathway.
Juha Klefstrom , Emmy W. Verschuren , Gerard Evan
Journal of Biological Chemistry 277 ( 45) 43224 -43232
72
2002
Therapeutic stratification of triple negative breast cancer by integrating chemosensitivity & phosphoproteome profiles
Prson Gautam , Xiangju Qin , Julia Vainonen , Srikar Nagelli
CANCER RESEARCH 80 ( 4)
2020
Pro-apoptotic functions of AMPK revealed by Myc
Heidi M Haikala , Elsa Marques , Vilja Eskelinen , Anni Viheriaranta-Nieminen
MOLECULAR CANCER RESEARCH 13
2015
An integrated approach for functional analysis of 11q13 amplification target genes in HNSCC
Tatiana Lepikhova , Henna Pehkonen , Riku Louhimo , Ping Chen
Cancer Research 71 ( 8_Supplement) 4963 -4963
2011
Discovery of selective matriptase and hepsin serine protease inhibitors: useful chemical tools for cancer cell biology
Vishnu C Damalanka , Zhenfu Han , Partha Karmakar , Anthony J O’Donoghue
Journal of medicinal chemistry 62 ( 2) 480 -490
29
2018
Induction of TNF‐sensitive cellular phenotype by c‐Myc involves p53 and impaired NF‐κB activation
Juha Klefstrom , Elena Arighi , Trevor Littlewood , Marja Jäättelä
The EMBO journal
144
1997
Impact of epithelial organization on Myc expression and activity
Johanna I Partanen , Juha Klefstrom
Cancer research 72 ( 4) 1035 -1035
1
2012
Combinations of metformin and BH3-mimetic drugs synergistically induce immunogenic cell death in breast cancer cells
Mariel Savelius , Linda Id , Johanna Anttila , Ruixian Liu
CANCER RESEARCH 84 ( 3)
2024
Myc synthetic lethality as a therapeutic strategy for resistance: Insights into the targetability of mitochondrial complex I in Myc-high TNBC
Antti O Hiltunen , Linda J Id , Juha Klefstrom
CANCER RESEARCH 84 ( 3)
2024
Patient derived explant culture (PDEC) as a model for treatment resistant ERα positive breast cancers
Pauliina Munne , Iiris Räty , Aino Peura , Linda Patrikainen
Cancer Research 82 ( 12_Supplement) 286 -286
2022
Abstract LB-204: Oncogenic Ras signaling requires serine protease hepsin to induce invasive breast cancer phenotype
Shishir Mani Pant , Topi Tervonen , Denis Belitskin , Johanna Englund
Cancer Research 80 ( 16_Supplement) LB -LB
2020
Functional genomic screen to identify candidates capable of modulating invasive properties of HNSCC
Tatiana N Lepikhova , Misa Imai , Nina Peitsaro , Juha Klefstrom
Cancer Research 70 ( 8_Supplement) 2192 -2192
2010
Abstract# 2267: Role of S1 transmembrane serine proteases in oncogenic transformation
Misa Imai , Topi Tervonen , Juha Klefstrom
Cancer Research 69 ( 9_Supplement) 2267 -2267
2009
Oncogenes as Regulators of Tumor Necrosis Factor Induced Cell Death
Juha Klefstrom
Univ., Molecular/Cancer Biology Laboratory
1997
Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity.
J. I. Partanen , T. A. Tervonen , M. Myllynen , E. Lind
Proceedings of the National Academy of Sciences of the United States of America 109 ( 7) 2196 -2197
78
2012
Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis
A. I. Nieminen , V. M. Eskelinen , H. M. Haikala , T. A. Tervonen
Proceedings of the National Academy of Sciences of the United States of America 110 ( 20) 7976 -7977
140
2013
Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization.
J. I. Partanen , A. I. Nieminen , T. P. Makela , J. Klefstrom
Proceedings of the National Academy of Sciences of the United States of America 104 ( 37) 14694 -14699
87
2007
c-Myc induces cellular susceptibility to the cytotoxic action of TNF-alpha.
J. Klefstrom , I. Västrik , E. Saksela , J. Valle
The EMBO Journal 13 ( 22) 5442 -5450
132
1994
Patient-Derived Explant Cultures (PDECs) as a Model System for Immuno-Oncology Studies
R. Turpin , P.M. Munne , I. Suleymanova , S. Mustjoki
Annals of Oncology 30
1
2019