Raccourcissement des télomères, sénescence cellulaire et télomérase
P. Dumont , O. Toussaint
La Revue de gériatrie 26 ( 9) 719 -728
2001
Pourquoi et comment vieillissons-nous : les théories du vieillissement
O. Toussaint , P. Dumont
La Revue de gériatrie 26 ( 8) 667 -672
2001
Decreasing Galectin-1 Expression in Human Hs683 Glioblastoma Cells Impairs their Response to Endoplasmic Reticulum Stress
Benjamin Haibe-Kains , Florence Lefranc , Christine Decaestecker , Isabelle Camby
Proceedings of the Belgium Society for Cell and Developmental Biology Autumn Meeting: Cytoskeleton and Cellular Imaging 23
2007
UNBS3157, a new amonafide derivative with improved in vivo efficacy and decreased toxicity
Eric Van Quaquebeke , Robert Kiss , Fabrice Ribaucour , Francis Darro
Cancer Research 66 1105 -1105
2006
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.
Eric Van Quaquebeke , Tine Mahieu , Patrick Dumont , Janique Dewelle
Journal of Medicinal Chemistry 50 ( 17) 4122 -4134
113
2007
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential.
Patrick Dumont , J. I-Ju Leu , Anthony C. Della Pietra , Donna L. George
Nature Genetics 33 ( 3) 357 -365
1,064
2003
The Codon 47 Polymorphism in p53 Is Functionally Significant
Xiaoxian Li , Patrick Dumont , Anthony Della Pietra , Cory Shetler
Journal of Biological Chemistry 280 ( 25) 24245 -24251
94
2005
Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast
Patrick Dumont , Maggi Burton , Qin M Chen , Efstathios S Gonos
Free Radical Biology and Medicine 28 ( 3) 361 -373
436
2000
Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide
Patrick Dumont , Florence Chainiaux , François Eliaers , Chariklia Petropoulou
Cell Stress & Chaperones 7 ( 1) 23 -35
74
2002
Expression of galectin-3 in the tumor immune response in colon cancer
Patrick Dumont , Alix Berton , Nathalie Nagy , Flavienne Sandras
Laboratory Investigation 88 ( 8) 896 -906
31
2008
Stress-induced premature senescence as alternative toxicological method for testing the long-term effects of molecules under development in the industry.
Olivier Toussaint , Patrick Dumont , Jean-François Dierick , Thierry Pascal
Biogerontology 1 ( 2) 179 -183
27
2000
Stress-Induced Premature Senescence or Stress-Induced Senescence-Like Phenotype: One In Vivo Reality, Two Possible Definitions?
Olivier Toussaint , Patrick Dumont , Jose Remacle , Jean-Francois Dierick
The Scientific World Journal 2 230 -247
62
2002
Decrease of mitochondrial p53 during late apoptosis is linked to its dephosphorylation on serine 20
Cédric Castrogiovanni , Marie Vandaudenard , Béranger Waterschoot , Olivier De Backer
Cancer Biology & Therapy 16 ( 9) 1296 -1307
8
2015
Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers
Tatjana Mijatovic , Véronique Mathieu , Jean-François Gaussin , Nancy De Néve
Neoplasia 8 ( 5) 402 -412
120
2006
The Amaryllidaceae Isocarbostyril Narciclasine Induces Apoptosis By Activation of the Death Receptor and/or Mitochondrial Pathways in Cancer Cells But Not in Normal Fibroblasts
Patrick Dumont , Laurent Ingrassia , Sébastien Rouzeau , Fabrice Ribaucour
Neoplasia 9 ( 9) 766 -776
191
2007
Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress-induced premature senescence
Patrick Dumont , Véronique Royer , Thierry Pascal , Jean-François Dierick
FEBS Letters 502 ( 3) 109 -112
64
2001
Resveratrol induces DNA damage in colon cancer cells by poisoning topoisomerase II and activates the ATM kinase to trigger p53-dependent apoptosis.
Benjamin Demoulin , Maryse Hermant , Cédric Castrogiovanni , Catherine Staudt
Toxicology in Vitro 29 ( 5) 1156 -1165
80
2015
The tetramerization domain of p53 is required for efficient BAK oligomerization
Donna L. George , Maureen E. Murphy , E. Christine Pietsch , J. I-Ju Leu
Cancer Biology & Therapy 6 ( 10) 1576 -1583
38
2007
Wild-type and mutant p53 proteins interact with mitochondrial caspase-3
Amanda K. Frank , E. Christine Pietsch , Patrick Dumont , Joy Tao
Cancer Biology & Therapy 11 ( 8) 740 -745
53
2011
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
J. I-Ju Leu , Patrick Dumont , Michael Hafey , Maureen E. Murphy
Nature Cell Biology 6 ( 5) 443 -450
965
2004