Novel gene delivery systems for brain targeting

Sukrut Somani
University of Strathclyde

2015
Targeted non-viral gene therapy in prostate cancer

Christine Dufès , Sukrut Somani , Najla Altwaijry
International Journal of Nanomedicine

2018
Tumor regression after intravenous administration of plumbagin entrapped in transferrin-conjugated, lipid–polymer hybrid nanoparticles

Christine Dufès , Sukrut Somani , Margaret Mullin , Partha Laskar
International Journal of Nanomedicine

2021
Regression of melanoma following intravenous injection of plumbagin entrapped in transferrin-conjugated, lipid–polymer hybrid nanoparticles

Christine Dufès , Sukrut Somani , Margaret Mullin , Partha Laskar
International Journal of Nanomedicine 16 2615 -2631

10
2021
Development of transferrin-bearing vesicles encapsulating aspirin for cancer therapy

Intouch Sakpakdeejaroen , Sukrut Somani , Margaret Mullin , Christine Dufès
Journal of Liposome Research 30 ( 2) 174 -181

2020
Proof of concept studies for siRNA delivery by nonionic surfactant vesicles: in vitro and in vivo evaluation of protein knockdown.

Mohammad A. Obeid , Christine Dufès , Sukrut Somani , Alexander B. Mullen
Journal of Liposome Research 29 ( 3) 229 -238

8
2019
Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes

Li Ying Lim , Pei Yin Koh , Sukrut Somani , Majed Al Robaian
Nanomedicine: Nanotechnology, Biology and Medicine 11 ( 6) 1445 -1454

29
2015
Anti-Tumor Activity of Intravenously Administered Plumbagin Entrapped in Targeted Nanoparticles.

Intouch Sakpakdeejaroen , Sukrut Somani , Partha Laskar , Craig Irving
Journal of Biomedical Nanotechnology 16 ( 1) 85 -100

2
2020
19
2018
Transferrin and the transferrin receptor for the targeted delivery of therapeutic agents to the brain and cancer cells

Christine Dufès , Majed Al Robaian , Sukrut Somani
Therapeutic Delivery 4 ( 5) 629 -640

66
2013
Enhanced gene expression in the brain following intravenous administration of lactoferrin-bearing polypropylenimine dendriplex

Sukrut Somani , Gillian Robb , Benjamin S Pickard , Christine Dufès
Journal of Controlled Release 217 235 -242

23
2015
Transferrin-bearing polypropylenimine dendrimer for targeted gene delivery to the brain

Sukrut Somani , David R Blatchford , Owain Millington , M Lynn Stevenson
Journal of Controlled Release 188 78 -86

54
2014
Redox-sensitive, cholesterol-bearing PEGylated poly(propylene imine)-based dendrimersomes for drug and gene delivery to cancer cells.

Partha Laskar , Sukrut Somani , Najla Altwaijry , Margaret Mullin
Nanoscale 10 ( 48) 22830 -22847

11
2018
Camptothecin-based dendrimersomes for gene delivery and redox-responsive drug delivery to cancer cells

Partha Laskar , Sukrut Somani , Sara Jane Campbell , Margaret Mullin
Nanoscale 11 ( 42) 20058 -20071

13
2019
Repurposing screen identifies mebendazole as a clinical candidate to synergise with docetaxel for prostate cancer treatment

Linda K. Rushworth , Kay Hewit , Sophie Munnings-Tomes , Sukrut Somani
British Journal of Cancer 122 ( 4) 517 -527

7
2020
Applications of dendrimers for brain delivery and cancer therapy

Sukrut Somani , Christine Dufès
Nanomedicine: Nanotechnology, Biology and Medicine 9 ( 15) 2403 -2414

42
2014
Transferrin-bearing dendrimers for cancer therapy: an update.

Sukrut Somani , Christine Dufès
Nanomedicine: Nanotechnology, Biology and Medicine 10 ( 14) 2125 -2127

5
2015
PEGylation of polypropylenimine dendrimers : effects on cytotoxicity, DNA condensation, gene delivery and expression in cancer cells

Sukrut Somani , Partha Laskar , Najla Altwaijry , Paphitchaya Kewcharoenvong
Scientific Reports 8 ( 1) 9410 -9410

27
2018
Tumor regression after intravenous administration of targeted vesicles entrapping the vitamin E α-tocotrienol

Reatul Karim , Sukrut Somani , Majed Al Robaian , Margaret Mullin
Journal of Controlled Release 246 79 -87

20
2017