Transferrin-bearing dendrimers for cancer therapy: an update.

作者: Sukrut Somani , Christine Dufès

DOI: 10.2217/NNM.15.93

关键词: CancerNanomedicineTumor targetingBioinformaticsTransferrinCancer cellMedicineGenetic enhancementPharmacologyDendrimerCancer therapy

摘要: Recent advances in multi-disciplinary research have resulted the emergence of an increasing number promising therapeutic strategies against cancer. However, intravenous administration these drugs is often limited by their inability to specifically reach tumors, thus resulting damaging secondary effects on healthy tissues. In order remediate this problem, a wide range delivery systems been investigated, aiming target cancer cells and deliver cargo pathological site. Among them, transferrin-bearing dendrimers are emerging as highly non-viral vectors for efficiently delivering nucleic acids cells. The focus editorial provide update being made so far when using targeted systems.

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