Dendrimers: Smart nanoengineered polymers for bioinspired applications in drug delivery
作者： Keerti Jain , None
DOI: 10.1016/B978-0-08-101914-6.00007-7
关键词:
摘要: Abstract Dendrimers have attracted growing attention in the field of drug delivery as smart nanoengineered polymers. They are defined novel three-dimensional polymers with nearly monodispersed architectures well-defined size and shape. synthesized by step-by-step controlled chemical reactions. Because their unique properties, exclusive synthesis methods, distinctive architecture, monodispersity, physicochemical dendrimers emerging smart, tailor-made, safe, effective for biomedical applications. In current scenario extensively being investigated bioinspired various applications to achieve well develop personalized medicine systems. shown potential intracellular vector therapeutic concentration at cellular targets enhanced specificity. Furthermore, also applicability tissue engineering. been explored targeted a large number bioactives, including anticancer drugs, antiviral antileishmanial small interfering RNA, gene, antigens, diagnostic contrast agents. Unmodified surface cationic groups may elicit some toxic manifestations, engineering mask these plays critical role possible clinical rendering them more biocompatible less toxicity. vast array applications, this chapter we given an account on aspects polymer, particularly relevance its
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