Derek Claxton
机构: Assistant Prof, Vanderbilt University
每年引用次数
引用次数
引用: 1,367
H-指数: 16
I10-指数 : 19
出版物: 33
Conformational Cycle Of A Bacterial Homolog Of Human Neurotransmitter Sodium Symporters
Derek Claxton , Matthias Quick , Lei Shi , Lynn Chung
Biophysical Journal 96 ( 3)
1
2009
Structure and Mechanism of a Bacterial Homolog of Neurotransmitter: sodium Symporters
Derek Paul Claxton
Vanderbilt University
2010
Crystallization papers-Purification, crystallization and preliminary X-ray analysis of Caenorhabditis elegans ubiquitin-conjugation enzyme M7. 1-Here, the cloning, expression, purification and
JA Gavira , DP Claxton , JH Wang , D Toh
Acta Crystallographica-Section D 59 ( 3) 544 -546
2003
Principles of alternating access in multidrug and toxin extrusion (MATE) transporters
Hassane S. Mchaourab , Derek P. Claxton , Kevin L. Jagessar
Journal of Molecular Biology 166959 -166959
2021
Sodium and proton coupling in the conformational cycle of a MATE antiporter from Vibrio cholerae.
Derek P. Claxton , Kevin L. Jagessar , P. Ryan Steed , Richard A. Stein
Proceedings of the National Academy of Sciences of the United States of America 115 ( 27)
19
2018
Structure and assembly of CAV1 8S complexes revealed by single particle electron microscopy.
Bing Han , Jason C. Porta , Jessica L. Hanks , Yelena Peskova
Science Advances 6 ( 49)
3
2020
The N-terminal domain of an archaeal multidrug and toxin extrusion (MATE) transporter mediates proton coupling required for prokaryotic drug resistance.
Kevin L. Jagessar , Hassane S. Mchaourab , Derek P. Claxton
Journal of Biological Chemistry 294 ( 34) 12807 -12814
6
2019
Sequence and Structural Determinants of Ligand-dependent Alternating Access of a MATE Transporter
Kevin L. Jagessar , Derek P. Claxton , Richard A. Stein , Hassane S. Mchaourab
bioRxiv 773572
2019
Structure and Orientation of T4 Lysozyme Bound to the Small Heat Shock Protein α-Crystallin
Derek P. Claxton , Ping Zou , Hassane S. Mchaourab
Journal of Molecular Biology 375 ( 4) 1026 -1039
24
2008
Purification, crystallization and preliminary X-ray analysis of Caenorhabditis elegans ubiquitin-conjugation enzyme M7.1.
José A. Gavira , Derek P. Claxton , Jenny H. Wang , Diana Toh
Acta Crystallographica Section D-biological Crystallography 59 ( 3) 544 -546
2003
Disulfide cross-links in the interaction of a cataract-linked αA-crystallin mutant with βB1-crystallin
M. Satish Kumar , Hanane A. Koteiche , Derek P. Claxton , Hassane S. Mchaourab
FEBS Letters 583 ( 1) 175 -179
15
2009
Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter.
Kevin L. Jagessar , Derek P. Claxton , Richard A. Stein , Hassane S. Mchaourab
Proceedings of the National Academy of Sciences of the United States of America 117 ( 9) 4732 -4740
5
2020
Species-Specific Structural and Functional Divergence of α-Crystallins: Zebrafish αBa- and Rodent αA(ins)-Crystallin Encode Activated Chaperones.
Hanane A. Koteiche , Derek P. Claxton , Sanjay Mishra , Richard A. Stein
Biochemistry 54 ( 38) 5949 -5958
7
2015
Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na+ in ion-coupled drug efflux
Steven Castellano , Derek P. Claxton , Emel Ficici , Tsukasa Kusakizako
Journal of Biological Chemistry 296 100262 -100262
2
2021
Engineering of a Polydisperse Small Heat-Shock Protein Reveals Conserved Motifs of Oligomer Plasticity
Sanjay Mishra , Shane A. Chandler , Dewight Williams , Derek P. Claxton
Structure 26 ( 8) 1116 -1126.e4
6
2018
Revealing the Transport Cycle Dynamics of the Sodium Dependent Sugar Transporter by Double Electron-Electron Resonance and Wide-Angle X-ray Scattering
Aviv Paz , Derek P. Claxton , Shruti Sharma , Kelli Kazmier
Biophysical Journal 110 ( 3) 222a
2016
Navigating Membrane Protein Structure, Dynamics, and Energy Landscapes Using Spin Labeling and EPR Spectroscopy.
Derek P. Claxton , Kelli Kazmier , Smriti Mishra , Hassane S. Mchaourab
Methods in Enzymology 564 349 -387
34
2015
Conformational transitions of the sodium-dependent sugar transporter, vSGLT.
Aviv Paz , Derek P. Claxton , Jay Prakash Kumar , Kelli Kazmier
Proceedings of the National Academy of Sciences of the United States of America 115 ( 12)
17
2018
Expression and purification of a functional heteromeric GABAA receptor for structural studies.
Derek P. Claxton , Eric Gouaux
PLOS ONE 13 ( 7)
4
2018
Alternating access mechanisms of LeuT-fold transporters: trailblazing towards the promised energy landscapes.
Kelli Kazmier , Derek P Claxton , Hassane S Mchaourab
Current Opinion in Structural Biology 45 100 -108
34
2017