Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN -amplified neuroblastoma.

Cyril H Benes , Timothy L Lochmann , Patricia Greninger , Anthony C Faber
Proceedings of the National Academy of Sciences of the United States of America 118 ( 13)

2021
Venetoclax-based rational combinations are effective in models of MYCN-amplified neuroblastoma.

Yaël P Mossé , Cyril H Benes , Patricia Greninger , Renata Sano
Molecular Cancer Therapeutics

2021
Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways

S Michael Rothenberg , Kyle Concannon , Sarah Cullen , Gaylor Boulay
eLife 4

28
2015
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

Aaron N Hata , Matthew J Niederst , Hannah L Archibald , Maria Gomez-Caraballo
Nature Medicine 22 ( 3) 262 -269

480
2016
Classification of gastrointestinal stromal tumor syndromes.

Priya Gopie , Lin Mei , Anthony C Faber , Steven R Grossman
Endocrine-related Cancer 25 ( 2)

15
2018
BCL-2 inhibition is a promising therapeutic strategy for small cell lung cancer.

Timothy L Lochmann , Ynes M Bouck , Anthony C Faber
Oncoscience 5 218 -219

16
2018
High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition

Jinyang Cai , Sheeba Jacob , Richard Kurupi , Krista M Dalton
Cell reports 40 ( 4)

7
2022
BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors

Anthony C Faber , Ryan B Corcoran , Hiromichi Ebi , Lecia V Sequist
Cancer discovery 1 ( 4) 352 -365

334
2011
Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6 dependent survival pathways

Stephen Michael Rothenberg , Kyle Concannon , Sarah Cullen , Alexa B Turke
Cancer Research 74 ( 19_Supplement) 4773 -4773

2014
Rapid assessment of TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF mutant melanoma.

Ryan B Corcoran , Stephen M Rothenberg , Aaron N Hata , Anthony C Faber
Cancer Research 73 ( 8_Supplement) 4568 -4568

2013
MYCN upregulates the transsulfuration pathway to suppress the ferroptotic vulnerability in MYCN-amplified neuroblastoma

Konstantinos V Floros , Ayesha T Chawla , Mia O Johnson-Berro , Rishabh Khatri
Cell Stress 6 ( 2) 21 -21

11
2022
Pharmaceutical interference of the EWS-FLI1–driven transcriptome by cotargeting H3K27ac and RNA polymerase activity in Ewing sarcoma

Daniel AR Heisey , Sheeba Jacob , Timothy L Lochmann , Richard Kurupi
Molecular Cancer Therapeutics 20 ( 10) 1868 -1879

10
2021
Pharmacologic inhibition of SHP2 blocks both PI3K and MEK signaling in low-epiregulin HNSCC via GAB1

Richard Kurupi , Konstantinos V Floros , Sheeba Jacob , Ayesha T Chawla
Cancer research communications 2 ( 9) 1061 -1074

4
2022
Exploring the relationship between metabolism and the epigenome in MYCN-amplified neuroblastoma

Krista M Dalton , Timothy L Lochmann , Colin Coon , Marissa L Calbert
Cancer Research 84 ( 6_Supplement) 5119 -5119

2024
R9: A novel NuRD complex inhibitor for targeted therapy in triple negative breast cancer (TNBC)

Kun Zhang , Sheeba Jacob , Mikhail Dozmorov , Ivan Babic
Cancer Research 84 ( 6_Supplement) 5976 -5976

2024