引用次数
引用: 2,848
H-指数: 28
I10-指数 : 104
出版物: 261
Synthesis of 5′-Terminal Capped Oligonucleotides Using O–N Phosphoryl Migration of Phosphoramidite Derivatives
Akihiro Ohkubo , Nobuhiro Tago , Akira Yokouchi , Yudai Nishino
Organic Letters 14 ( 1) 10 -13
10
2012
Short-RNA selective binding of oligonucleotides modified using adenosine and guanosine derivatives that possess cyclohexyl phosphates as substituents.
Kohji Seio , Sayako Kurohagi , Erika Kodama , Yoshiaki Masaki
Organic and Biomolecular Chemistry 10 ( 5) 994 -1006
3
2012
Synthesis and triplex-forming properties of oligonucleotides capable of recognizing corresponding DNA duplexes containing four base pairs
Akihiro Ohkubo , Kenji Yamada , Yu Ito , Kiichi Yoshimura
Nucleic Acids Research 43 ( 12) 5675 -5686
20
2015
Fluorescent pyrimidopyrimidoindole nucleosides: control of photophysical characterizations by substituent effects.
Masahiro Mizuta , Kohji Seio , Kenichi Miyata , Mitsuo Sekine
Journal of Organic Chemistry 72 ( 14) 5046 -5055
47
2007
Synthesis and fluorescent properties of bi- and tricyclic 4-N-carbamoyldeoxycytidine derivatives.
Kenichi Miyata , Ryota Mineo , Ryuji Tamamushi , Masahiro Mizuta
Journal of Organic Chemistry 72 ( 1) 102 -108
21
2007
Synthesis of TMG-capped RNA–DNA chimeric oligonucleotides
Mitsuo Sekine , Masatoshi Ushioda , Takeshi Wada , Kohji Seio
Tetrahedron Letters 44 ( 8) 1703 -1707
6
2003
Prediction of the stability of modified RNA duplexes based on deformability analysis: oligoribonucleotide derivatives modified with 2′-O-cyanoethyl-5-propynyl-2-thiouridine as a promising component
Yoshiaki Masaki , Ryuta Miyasaka , Kunihiro Hirai , Hirosuke Tsunoda
Chemical Communications 48 ( 58) 7313 -7315
11
2012
A New Route to 2‘-O-Alkyl-2-thiouridine Derivatives via 4-O-Protection of the Uracil Base and Hybridization Properties of Oligonucleotides Incorporating These Modified Nucleoside Derivatives
Itaru Okamoto , Koh-ichiroh Shohda , Kohji Seio , Mitsuo Sekine
Journal of Organic Chemistry 68 ( 26) 9971 -9982
25
2003
Synthesis of chemically stabilized phosmidosine analogues and the structure--activity relationship of phosmidosine.
Mitsuo Sekine , Kazuhisa Okada , Kohji Seio , Hideaki Kakeya
Journal of Organic Chemistry 69 ( 2) 314 -326
13
2004
Proton-block strategy for the synthesis of oligodeoxynucleotides without base protection, capping reaction, and P-N bond cleavage reaction.
Mitsuo Sekine , Akihiro Ohkubo , Kohji Seio
Journal of Organic Chemistry 68 ( 14) 5478 -5492
40
2003
Computational evaluation of the stability of 2'-O-methyl-RNA/RNA duplexes incorporating 3-deazaguanine derivatives by ab initio calculations and a molecular dynamics simulation
Takeshi Sasami , Ryuya Tawarada , Akihiro Ohkubo , Mitsuo Sekine
Journal of Molecular Structure-theochem 899 ( 1) 54 -60
3
2009
Novel EGFP reporter cell and mouse models for sensitive imaging and quantification of exon skipping
Yuko Hara , Yoshitaka Mizobe , Yukiko U. Inoue , Yasumasa Hashimoto
Scientific Reports 10 ( 1) 10110
1
2020
Synthesis of oligodeoxyribonucleotides containing hydroxymethylphosphonate bonds in the phosphoramidite method and their hybridization properties
Akihiro Ohkubo , Katsufumi Aoki , Yusuke Ezawa , Yuichi Sato
Tetrahedron Letters 46 ( 51) 8953 -8957
13
2005
Improved synthesis of oligonucleotides containing 2-thiouridine derivatives by use of diluted iodine solution
Itaru Okamoto , Kohji Seio , Mitsuo Sekine
Tetrahedron Letters 47 ( 4) 583 -585
16
2006
1,1-Dihydroperoxycyclododecane as a new, crystalline non-hygroscopic oxidizer for the chemical synthesis of oligodeoxyribonucleotides
Hisao Saneyoshi , Kenichi Miyata , Kohji Seio , Mitsuo Sekine
Tetrahedron Letters 47 ( 50) 8945 -8947
9
2006
Synthesis of pentathymidylate using a 4-monomethoxytritylthio (MMTrS) group as a 5′-hydroxyl protecting group: toward oligonucleotide synthesis without acid treatment
Kohji Seio , Mitsuo Sekine
Tetrahedron Letters 42 ( 49) 8657 -8660
11
2001
Solid-phase synthesis of a 5′-terminal TMG-capped trinucleotide block of U1 snRNA
Michinori Kadokura , Takeshi Wada , Kohji Seio , Tomohisa Moriguchi
Tetrahedron Letters 42 ( 50) 8853 -8856
21
2001
Effective Strategy for Conformer-Selective Detection of Short-Lived Excited State Species: Application to the IR Spectroscopy of the N1H Keto Tautomer of Guanine.
Hiroya Asami , Munefumi Tokugawa , Yoshiaki Masaki , Shun-ichi Ishiuchi
Journal of Physical Chemistry A 120 ( 14) 2179 -2184
4
2016
Synthesis and Properties of Conformationally Rigid Cyclouridylic Acids Having Covalent Bonding Linkers Between the Uracil 5-Position and the 5′-Phosphate Group
Kohji Seio , Osamu Kurasawa , Takeshi Wada , Kensaku Sakamoto
Nucleosides, Nucleotides & Nucleic Acids 16 1023 -1032
4
1997
Synthesis of artificially bent oligonucleotides by incorporation of conformationally rigid 5'-cyclouridylic acid derivatives
Mitsuo Sekine , Osamu Kurasawa , Kohji Seio , Koh-Ichiroh Shohda
Nucleosides, Nucleotides & Nucleic Acids 18 1163 -1168
1
1999