MS21. P08
J Soman , M Strader , W Hicks , T Kassa
Acta Cryst 70 C310 -C310
2014
Decreases the Redox Potential and Reactivity of-Subunits of Human HbA with Hydrogen Peroxide
Todd L Mollan , Sambuddha Banerjee , Gang Wu , Claire J Parker Siburt
J. Biol. Chem 2013 ( 288) 4288 -4298
2012
Familial secondary erythrocytosis due to increased oxygen affinity is caused by destabilization of the T state of hemoglobin Brigham (α2β2Pro100Leu)
Todd L. Mollan , Bindu Abraham , Michael Brad Strader , Yiping Jia
Protein Science 21 ( 10) 1444 -1455
3
2012
The Role of Alpha-Hemoglobin Stabilizing Protein in Redox Chemistry, Denaturation, and Hemoglobin Assembly
Todd L. Mollan , Xiang Yu , Mitchell J. Weiss , John S. Olson
Antioxidants & Redox Signaling 12 ( 2) 219 -231
31
2010
Development of Recombinant Hemoglobin-Based Oxygen Carriers
Cornelius L. Varnado , Todd L. Mollan , Ivan Birukou , Bryan J.Z. Smith
Antioxidants & Redox Signaling 18 ( 17) 2314 -2328
66
2013
Redox Reactions of Hemoglobin: Mechanisms of Toxicity and Control
Todd L. Mollan , Abdu I. Alayash
Antioxidants & Redox Signaling 18 ( 17) 2251 -2253
22
2013
Post-translational transformation of methionine to aspartate is catalyzed by heme iron and driven by peroxide: a novel subunit-specific mechanism in hemoglobin.
Michael Brad Strader , Wayne A. Hicks , Tigist Kassa , Eileen Singleton
Journal of Biological Chemistry 289 ( 32) 22342 -22357
23
2014
Kinetics of α-globin binding to α-hemoglobin stabilizing protein (AHSP) indicate preferential stabilization of hemichrome folding intermediate.
Todd L. Mollan , Eugene Khandros , Mitchell J. Weiss , John S. Olson
Journal of Biological Chemistry 287 ( 14) 11338 -11350
17
2012
Insights into hemoglobin assembly through in vivo mutagenesis of α-hemoglobin stabilizing protein.
Eugene Khandros , Todd L. Mollan , Xiang Yu , Xiaomei Wang
Journal of Biological Chemistry 287 ( 14) 11325 -11337
16
2012
Redox properties of human hemoglobin in complex with fractionated dimeric and polymeric human haptoglobin.
Todd L. Mollan , Yiping Jia , Sambuddha Banerjee , Gang Wu
Free Radical Biology and Medicine 69 265 -277
43
2014
A Hemoglobin Variant Associated with Neonatal Cyanosis and Anemia
Moira A. Crowley , Todd L. Mollan , Osheisa Y. Abdulmalik , Andrew D. Butler
The New England Journal of Medicine 364 ( 19) 1837 -1843
17
2011
α-Hemoglobin-stabilizing Protein (AHSP) Perturbs the Proximal Heme Pocket of Oxy-α-hemoglobin and Weakens the Iron-Oxygen Bond *
Claire F. Dickson , Anne M. Rich , William M. H. D'Avigdor , Daniel A. T. Collins
Journal of Biological Chemistry 288 ( 27) 19986 -20001
9
2013
α-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of α-subunits of human HbA with hydrogen peroxide.
Todd L. Mollan , Sambuddha Banerjee , Gang Wu , Claire J. Parker Siburt
Journal of Biological Chemistry 288 ( 6) 4288 -4298
25
2013
Analysis of human α globin gene mutations that impair binding to the α hemoglobin stabilizing protein
Xiang Yu , Todd L. Mollan , Andrew Butler , Andrew J. Gow
Blood 113 ( 23) 5961 -5969
34
2009
The Role of Alpha-Hemoglobin Stabilizing Protein in Human Hemoglobin Assembly
Todd Mollan
Rice University
3
2011