Estrogen and Recurrent UTI: What Are the Facts?
T. J. Hannan , T. M. Hooton , S. J. Hultgren
Science Translational Medicine 5 ( 190)
11
2013
Molecular and Epidemiologic Basis of Urinary Tract Infection in Women
Thomas J HANNAN , Scott J I-IULTGREN
Nova acta Leopoldina 98 ( 359-360) 131 -138
2008
Early Severe Inflammatory Responses to Uropathogenic E. coli Predispose to Chronic and Recurrent Urinary Tract Infection
Thomas J. Hannan , Indira U. Mysorekar , Chia S. Hung , Megan L. Isaacson-Schmid
PLOS Pathogens 6 ( 8)
171
2010
Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection.
Ann E. Lin , Federico C. Beasley , Joshua Olson , Nadia Keller
PLOS Pathogens 11 ( 4)
38
2015
Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner.
Valerie P. O’Brien , Denise A. Dorsey , Thomas J. Hannan , Scott J. Hultgren
PLOS Pathogens 14 ( 12)
14
2018
Subinhibitory Antibiotic Therapy Alters Recurrent Urinary Tract Infection Pathogenesis through Modulation of Bacterial Virulence and Host Immunity
Jean M. Macklaim , Gregory B. Gloor , Hassan Razvi , Gregor Reid
Mbio 6 ( 2)
45
2015
Dysregulation of Escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection
Kanna Nagamatsu , Thomas J. Hannan , Randi L. Guest , Maria Kostakioti
Proceedings of the National Academy of Sciences of the United States of America 112 ( 8) 201500374
73
2015
A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug resistant uropathogenic Escherichia coli ST131.
Makrina Totsika , Maria Kostakioti , Thomas J. Hannan , Mathew Upton
The Journal of Infectious Diseases 208 ( 6) 921 -928
96
2013
Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection.
Drew J. Schwartz , Matt S. Conover , Thomas J. Hannan , Scott J. Hultgren
PLOS Pathogens 11 ( 1)
33
2015
Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection.
Maria Kostakioti , Maria Hadjifrangiskou , Corinne K. Cusumano , Thomas J. Hannan
Infection and Immunity 80 ( 8) 2826 -2834
35
2012
Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic Escherichia coli bladder infection
Thomas J. Hannan , Makrina Totsika , Kylie J. Mansfield , Kate H. Moore
Fems Microbiology Reviews 36 ( 3) 616 -648
215
2012
Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.
Vasilios Kalas , Jerome S. Pinkner , Thomas J. Hannan , Michael E. Hibbing
Science Advances 3 ( 2)
27
2017
Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections.
Hailyn V. Nielsen , Scott J. Hultgren , Valerie P. O’Brien , Thomas J. Hannan
Microbiology spectrum 4 ( 1) 589 -646
56
2016
A Murine Model for Escherichia coli Urinary Tract Infection.
Thomas J. Hannan , David A. Hunstad
Methods of Molecular Biology 1333 159 -175
47
2016
Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis
Thomas J. Hannan , Pacita L. Roberts , Terrence E. Riehl , Sjoerd van der Post
EBioMedicine 1 ( 1) 46 -57
64
2014
Enterococcus faecalis Overcomes Foreign Body-Mediated Inflammation To Establish Urinary Tract Infections
Pascale S. Guiton , Thomas J. Hannan , Bradley Ford , Michael G. Caparon
Infection and Immunity 81 ( 1) 329 -339
50
2013
Are you experienced? Understanding bladder innate immunity in the context of recurrent urinary tract infection
Valerie P. O’Brien , Thomas J. Hannan , Anthony J. Schaeffer , Scott J. Hultgren
Current Opinion in Infectious Diseases 28 ( 1) 97 -105
26
2015
Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections
Henry L. Schreiber , Matt S. Conover , Wen-Chi Chou , Michael E. Hibbing
Science Translational Medicine 9 ( 382)
65
2017
Rational design strategies for FimH antagonists: new drugs on the horizon for urinary tract infection and Crohn’s disease
Laurel K. Mydock-McGrane , Thomas J. Hannan , James W. Janetka
Expert Opinion on Drug Discovery 12 ( 7) 711 -731
34
2017
Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence.
Lu Yu , Valerie P O'Brien , Jonathan Livny , Denise Dorsey
eLife 8
9
2019