EVALUATION OF DRUG RESPONSES IN NON-TRANSFORMED CELLS CARRYING CANCER ALLELES

Giovanni Battista Appendino , M Geuna , Enzo Medico , Roberto Fantozzi
34° Congresso Nazionale della Società Italiana di Farmacologia 14 -14

2009
Knock in of cancer mutations in human cells predicts pharmacologicalresponse to targeted therapies

Federica Di Nicolantonio , Margherita Gallicchio , Alberto Bardelli , Davide Zecchin
III CONVEGNO MONOTEMATICO SIF - FARMACOGENOMICA E CANCRO: DAL LABORATORIO ALLA CLINICA 14 -14

2011
Unveiling of BRAF V600E Mutant Cells Sensitivity to Proteasome Inhibitors Using an Isogenic Cell Based Screening

Federica Di Nicolantonio , Margherita Gallicchio , Alberto Bardelli , Davide Zecchin
36° CONGRESSO NAZIONALE DELLA SOCIETÀ ITALIANA DI FARMACOLOGIA 115 -115

2013
CD4 T cell dependent rejection of beta 2 microglobulin null mismatch repair deficient tumors.

Giovanni Germano , Steve Lu , Giuseppe Rospo , Simona Lamba
Cancer Discovery

1
2021
EGFR Amplification in Metastatic Colorectal Cancer.

Benedetta Mussolin , Massimo Milione , Gouri Nanjangud , Giovanni Randon
Journal of the National Cancer Institute

2021
Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ.

Michelangelo Cordenonsi , Silvio Bicciato , Andrea Cassingena , Claudio Tripodo
Nature Communications 12 ( 1) 2340 -2340

2021
Precision oncology in metastatic colorectal cancer - from biology to medicine.

Pietro Paolo Vitiello , Pietro Paolo Vitiello , Federica Di Nicolantonio , Livio Trusolino
Nature Reviews Clinical Oncology 1 -20

77
2021
2021
Adaptive Evolution: How Bacteria and Cancer Cells Survive Stressful Conditions and Drug Treatment.

Alberto Bardelli , Mariangela Russo , Alberto Sogari
Cancer Discovery

2021
Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors are associated with disease progression.

Stefano Biffo , Alessio Amatu , Sergio Abrignani , Jens Geginat
Nature Immunology 22 ( 6) 735 -745

2021
Mechanisms of Immune Escape and Resistance to Checkpoint Inhibitor Therapies in Mismatch Repair Deficient Metastatic Colorectal Cancers.

Alberto Bardelli , Andrea Sartore-Bianchi , Salvatore Siena , Gianluca Mauri
Cancers 13 ( 11) 2638

22
2021
Clinical and molecular landscape of metastatic colorectal cancer (mCRC) harboring ALK, ROS1, or NTRK 1, 2, 3 (NTRKs) rearrangements.

Filippo Pietrantonio , Federica Di Nicolantonio , Alexa Betzig Schrock , Jeeyun Lee
Journal of Clinical Oncology 35 589 -589

2017
Abstract IA18: Cancer evolution as a therapeutic target

Alberto Bardelli
Clinical Cancer Research 24

2018
Abstract B11: Whole-exome sequencing analysis of urine transrenal tumor DNA in metastatic colorectal cancer patients

Giovanni Crisafulli , Benedetta Mussolin , Andrea Cassingena , Monica Montone
Clinical Cancer Research 26

2020
Abstract IA13: Tracking and targeting colorectal cancer evolution

Alberto Bardelli
Clinical Cancer Research 26

2020
Molecular Mechanisms of Resistance to Cetuximab and Panitumumab in Colorectal Cancer

Alberto Bardelli , Salvatore Siena
Journal of Clinical Oncology 28 ( 7) 1254 -1261

565
2010
Abstract C68: Endogenous expression of an oncogenic PI3K mutation leads to epithelial‐mesenchymal transition (EMT) and invasiveness

Jeffrey J. Wallin , Jane Guan , Pete Haverty , Zora Modrusan
Molecular Cancer Therapeutics 8

2009
Abstract A70: Isogenic K-Ras mutant cancer cells: A novel platform for drug profiling.

John Goodall , Jessica Hunt , Zhiqiang Chen , Federica Di Nicolantonio
Molecular Cancer Therapeutics 10

2011