Ludovica Lospinoso Severini
机构: Postdoctoral fellow at Sapienza University of Rome
每年引用次数
引用次数
引用: 433
H-指数: 11
I10-指数 : 12
出版物: 16
A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth
Lospinoso Severini , Quaglio , Basili , Ghirga
Cancers 11 ( 10) 1518
17
2019
Specific Protein 1 and p53 Interplay Modulates the Expression of the KCTD-Containing Cullin3 Adaptor Suppressor of Hedgehog 2.
Elisabetta Ferretti , Marialaura Petroni , Gianluca Canettieri , Enrico De Smaele
Frontiers in Cell and Developmental Biology 9 638508 -638508
2021
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Paola Infante , Roberta Faedda , Flavia Bernardi , Francesca Bufalieri
Nature Communications 9 ( 1) 976 -976
29
2018
The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I
Francesca Bufalieri , Miriam Caimano , Ludovica Lospinoso Severini , Irene Basili
Cancers 12 ( 2) 321
15
2020
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma.
Paola Infante , Alessio Malfanti , Deborah Quaglio , Silvia Balducci
Cancer Letters 499 220 -231
18
2021
Targeting Hedgehog Signalling through the Ubiquitylation Process: The Multiple Roles of the HECT-E3 Ligase Itch
Paola Infante , Ludovica Lospinoso Severini , Flavia Bernardi , Francesca Bufalieri
Cells 8 ( 2) 98
9
2019
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.
Francesca Bufalieri , Paola Infante , Flavia Bernardi , Miriam Caimano
Nature Communications 10 ( 1) 3304 -3318
14
2019
The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma
Ludovica Lospinoso Severini , Francesca Ghirga , Francesca Bufalieri , Deborah Quaglio
Expert Opinion on Therapeutic Targets 24 ( 11) 1159 -1181
4
2020
DUBs Activating the Hedgehog Signaling Pathway: A Promising Therapeutic Target in Cancer
Francesca Bufalieri , Ludovica Lospinoso Severini , Miriam Caimano , Paola Infante
Cancers 12 ( 6) 1518
2
2020
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61.
Andrea Calcaterra , Valentina Iovine , Bruno Botta , Deborah Quaglio
Journal of Enzyme Inhibition and Medicinal Chemistry 33 ( 1) 349 -358
42
2018
Drug delivery systems for hedgehog inhibitors in the treatment of SHH-medulloblastoma
Miriam Caimano , Ludovica Lospinoso Severini , Elena Loricchio , Paola Infante
Frontiers in chemistry 9 688108
8
2021
SALL4 is a CRL3REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma
Ludovica Lospinoso Severini , Elena Loricchio , Shirin Navacci , Irene Basili
Cell Death & Differentiation 31 ( 2) 170 -187
2
2024
SMA-miRs (miR-181a-5p,-324-5p, and-451a) are overexpressed in spinal muscular atrophy skeletal muscle and serum samples
Emanuela Abiusi , Paola Infante , Cinzia Cagnoli , Ludovica Lospinoso Severini
elife 10 e68054 -e68054
15
2021
MEX3A is a new diagnostic, independent prognostic biomarker and a promising therapeutic target in gliomas
Francesca Bufalieri , Daniele Armocida , Antonino Cucinotta , Pietro Familiari
2024
Proteolysis-Targeting Chimera (PROTAC): Is the Technology Looking at the Treatment of Brain Tumors?
Ludovica Lospinoso Severini , Francesca Bufalieri , Paola Infante , Lucia Di Marcotullio
Frontiers in Cell and Developmental Biology 10 854352 -854352
10
2022
The RIG-I agonist M8 triggers cell death and natural killer cell activation in human papillomavirus-associated cancer and potentiates cisplatin cytotoxicity
Carlo Girone , Federica Calati , Irene Lo Cigno , Valentina Salvi
Cancer Immunology, Immunotherapy 72 ( 9) 3097 -3110
4
2023