Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2

Wan-Chen Tsai , Nathan C Gilbert , Amanda Ohler , Michelle Armstrong
Bioorganic & medicinal chemistry 46 116349 -116349

23
2021
Crystal Structure of the Naturally Fused Coral Lipoxygenase and Allene Oxide Synthase

Marcia Newcomer , Adam Dassey , Marc Niebuhr , Hiro Tsuruta
The FASEB Journal 22

2008
Structural and functional insights of human 5-lipoxygenase

Nathaniel Carson Gilbert
Louisiana State University and Agricultural & Mechanical College

1
2011
Inhibition of Fosfomycin Resistance Protein FosB from Gram-Positive Pathogens by Phosphonoformate

Skye Travis , Keith D Green , Nathaniel C Gilbert , Oleg V Tsodikov
Biochemistry 62 ( 1) 109 -117

2022
Epigenetics Inhibitor

Simona Pace , Kehong Zhang , Paul M Jordan , Rossella Bilancia

The structure of the SufS-SufE complex reveals interactions driving protected persulfide transfer in iron-sulfur cluster biogenesis

Rajleen K Gogar , Nidhi Chhikara , Minh Vo , Nathaniel C Gilbert
bioRxiv 2024.05. 23.595560 -2024.05. 23.595560

2024
Allosteric activation of 15‐lipoxygenase‐1 by boswellic acid induces the lipid mediator class switch to promote resolution of inflammation

Friedemann Börner , Simona Pace , Paul M Jordan , Jana Gerstmeier
Advanced Science 10 ( 6) 2205604 -2205604

16
2023
Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators

Lukas K Peltner , Lars Gluthmann , Friedemann Börner , Simona Pace
Cell Chemical Biology 30 ( 12) 1508 -1524. e7

7
2023
Helical remodeling augments 5-lipoxygenase activity in the synthesis of proinflammatory mediators

Eden M Gallegos , Tanner D Reed , Forge A Mathes , Nelson V Guevara
Journal of Biological Chemistry 298 ( 9)

10
2022
37
2021
The 1.85 Å structure of an 8 R-lipoxygenase suggests a general model for lipoxygenase product specificity

David B Neau , Nathaniel C Gilbert , Sue G Bartlett , William Boeglin
Biochemistry 48 ( 33) 7906 -7915

127
2009
Investigating membrane-binding properties of lipoxygenases using surface plasmon resonance

Denise L Rohlik , Ethan Patel , Nathaniel C Gilbert , Adam R Offenbacher
Biochemical and Biophysical Research Communications 670 47 -54

10
2023
Helical remodeling augments 5-lipoxygenase activity

Eden M Gallegos , Tanner D Reed , Forge A Mathes , Nelson Guevera
bioRxiv 2022.03. 31.486615 -2022.03. 31.486615

1
2022
Soluble and stable human 5-lipoxygenase

Marcia E Newcomer , Sue G Bartlett , Nathaniel C Gilbert

1
2014
Structure of a model lipid membrane oxidized by human 15-lipoxygenase-2

Jamil Nemri , Cosme Morales , Nathaniel C Gilbert , Jaroslaw Majewski
Biochemical and Biophysical Research Communications 737 150533 -150533

2024
Human 5‐Lipoxygenase

Marcia E Newcomer , Nathaniel C Gilbert , Max O Funk
Encyclopedia of Inorganic and Bioinorganic Chemistry

2011
Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators

Oliver Werz , Marcia E. Newcomer , Nathaniel C. Gilbert , Antonietta Rossi
Pharmacological Research 167 105556 -105556

1
2021