Antidepressant-like effect of ascorbic acid is associated with the modulation of mammalian target of rapamycin pathway

Morgana Moretti , Josiane Budni , Andiara Espíndola Freitas , Priscila Batista Rosa
Journal of Psychiatric Research 48 ( 1) 16 -24

48
2014
Vatairea macrocarpa Lectin (VML) Induces Depressive-like Behavior and Expression of Neuroinflammatory Markers in Mice

Filipe Marques Gonçalves , Andiara Espíndola Freitas , Tanara Vieira Peres , Débora Kurrle Rieger
Neurochemical Research 38 ( 11) 2375 -2384

14
2013
TNF-α-induced depressive-like phenotype and p38(MAPK) activation are abolished by ascorbic acid treatment.

Morgana Moretti , Josiane Budni , Andiara Espíndola Freitas , Vivian Binder Neis
European Neuropsychopharmacology 25 ( 6) 902 -912

28
2015
3
2023
Neuronal activity regulated pentraxin (narp) and GluA4 subunit of AMPA receptor may be targets for fluoxetine modulation.

Isabella A Heinrich , Andiara E Freitas , Ingrid AV Wolin , Ana Paula M Nascimento
Metabolic Brain Disease 36 ( 4) 711 -722

2021
Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling.

Priscila B Rosa , Luis EB Bettio , Vivian B Neis , Morgana Moretti
Purinergic Signalling 17 ( 2) 285 -301

2021
Involvement of PI3K, GSK-3β and PPARγ in the antidepressant-like effect of folic acid in the forced swimming test in mice.

Josiane Budni , Kelly R Lobato , Ricardo W Binfaré , Andiara E Freitas
Journal of Psychopharmacology 26 ( 5) 714 -723

45
2012
Agmatine potentiates antidepressant and synaptic actions of ketamine: Effects on dendritic arbors and spines architecture and Akt/S6 kinase signaling.

Andiara E Freitas , Isabella A Heinrich , Tainara M Moura , Daiane B Fraga
Experimental Neurology 333 113398

2
2020
α-Tocopherol administration produces an antidepressant-like effect in predictive animal models of depression

Kelly R Lobato , Chandra C Cardoso , Ricardo W Binfaré , Josiane Budni
Behavioural Brain Research 209 ( 2) 249 -259

56
2010
Ascorbic acid presents rapid behavioral and hippocampal synaptic plasticity effects.

Daiane B Fraga , Ana Paula Costa , Gislaine Olescowicz , Anderson Camargo
Progress in Neuro-psychopharmacology & Biological Psychiatry 96 109757 -109757

10
2020
Physical exercise stimulates hippocampal mTORC1 and FNDC5/irisin signaling pathway in mice: Possible implication for its antidepressant effect.

Karen Gruhn , Aline Siteneski , Anderson Camargo , Andiara E Freitas
Behavioural Brain Research 400 113040

1
2021
Agmatine abolishes restraint stress-induced depressive-like behavior and hippocampal antioxidant imbalance in mice.

Andiara E Freitas , Luis EB Bettio , Vivian B Neis , Danúbia B Santos
Progress in Neuro-psychopharmacology & Biological Psychiatry 50 143 -150

67
2014
Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice.

Andiara E Freitas , Javier Egea , Izaskun Buendia , Vanessa Gómez-Rangel
Molecular Neurobiology 53 ( 5) 3030 -3045

89
2016
Antidepressant-like action of the ethanolic extract from Tabebuia avellanedae in mice: Evidence for the involvement of the monoaminergic system

Andiara E Freitas , Josiane Budni , Kelly R Lobato , Ricardo W Binfaré
Progress in Neuro-Psychopharmacology and Biological Psychiatry 34 ( 2) 335 -343

59
2010
Fluoxetine modulates hippocampal cell signaling pathways implicated in neuroplasticity in olfactory bulbectomized mice.

Andiara E Freitas , Daniele G Machado , Josiane Budni , Vivian B Neis
Behavioural Brain Research 237 176 -184

48
2013
Antidepressant-like effect of α-tocopherol in a mouse model of depressive-like behavior induced by TNF-α

Luana M Manosso , Vivian B Neis , Morgana Moretti , Juliana F Daufenbach
Progress in Neuro-psychopharmacology & Biological Psychiatry 46 48 -57

39
2013
Depressive-like behavior induced by tumor necrosis factor-α is abolished by agmatine administration.

Vivian Binder Neis , Luana Meller Manosso , Morgana Moretti , Andiara E Freitas
Behavioural Brain Research 261 336 -344

46
2014
Guanosine prevents behavioral alterations in the forced swimming test and hippocampal oxidative damage induced by acute restraint stress.

Luis EB Bettio , Andiara E Freitas , Vivian B Neis , Danúbia B Santos
Pharmacology, Biochemistry and Behavior 127 7 -14

66
2014