Use of partly known substituted pyrrolidine derivatives as pharmaceuticals, new compounds and process for their preparation
作者： Franz Dr. Kunisch , Joachim Dr. Mittendorf , Manfred Dr. Plempel , Hans-Christian Dr. Militzer
DOI:
关键词: Organic chemistry 、 Combinatorial chemistry 、 Chemistry 、 Process (engineering) 、 Meaning (existential) 、 Pyrrolidine
摘要: The present invention relates to substituted pyrrolidines of the general formula (I) in which A, B, R1, R2, R3, D and R4 have meaning given description, use pyrrolidines, some are known, as pharmaceuticals, particular antimycotic agents, new active compounds a process for their preparation.
lens.org 参考文章(4)
C. Gallina, C. Marta, C. Colombo, A. Romeo, Capreomycidine and 3-guanidinoproline from viomycidine Tetrahedron. ,vol. 27, pp. 4681- 4685 ,(1971) , 10.1016/S0040-4020(01)98175-X
Johannes Häusler, Darstellung voncis- undtrans-C-3-substituierten Prolinverbindungen Liebigs Annalen der Chemie. ,vol. 1981, pp. 1073- 1088 ,(1981) , 10.1002/JLAC.198119810613
O. M. Larsson, P. Thorbek, P. Krogsgaard-Larsen, A. Schousboe, Effect of Homo‐β‐Proline and Other Heterocyclic GAB A Analogues on GABA Uptake in Neurons and Astroglial Cells and on GABA Receptor Binding Journal of Neurochemistry. ,vol. 37, pp. 1509- 1516 ,(1981) , 10.1111/J.1471-4159.1981.TB06320.X
Carl W. Cotman, A. Richard Chamberlin, Mark S. Stanley, Richard J. Bridges, Method of inhibiting the transport of l-glutamate ,(1990)