Pyrrolidinyl di-carboxylic acid derivatives as metabotropic glutamate receptor antagonists

作者: James Allen Monn , Darryle Darwin Schoepp , Matthew John Valli

DOI:

关键词:

摘要: The present invention provides substituted pyrrolidines that affect certain excitatory amino acid receptors, and are useful in the treatment of neurological disorders psychiatric disorders. Specifically, compounds active as agonists metabotropic glutamate receptor subtype mGluR2.

参考文章(2)
Carl W. Cotman, A. Richard Chamberlin, Mark S. Stanley, Richard J. Bridges, Method of inhibiting the transport of l-glutamate ,(1990)
Franz Dr. Kunisch, Joachim Dr. Mittendorf, Manfred Dr. Plempel, Hans-Christian Dr. Militzer, Use of partly known substituted pyrrolidine derivatives as pharmaceuticals, new compounds and process for their preparation ,(1992)