1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h,1'h-[1,4']bipyridinyl-2'-ones
作者： Andres Avelino Trabanco-Suarez , Guillaume Albert Jacques Duvey , Robert Johannes Lütjens , Gregor James MacDonald , Jose Maria Cid-Nunez
DOI:
关键词:
摘要: wherein all radicals are as defined in the application and claims. The compounds according to invention positive allosteric modulators of metabotropic receptors—subtype 2 (“mGluR2”) which useful for treatment or prevention neurological psychiatric disorders associated with glutamate dysfunction diseases mGluR2 subtype receptors is involved. In particular, such central nervous system selected from group anxiety, schizophrenia, migraine, depression, epilepsy. also directed pharmaceutical compositions processes prepare compositions, well use
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