The evaluation and comparison of consecutive high speed centrifugation and LipoClear® reagent for lipemia removal

摘要: Abstract Background The aim of this study was to evaluate and compare the efficiency high speed centrifugation LipoClear® reagent for lipemia removal in plasma samples spiked with Intralipid®, 26 biochemistry analytes. Materials methods A pool collected. Aliquots were Intralipid® (final concentrations 300 mg/dL 500 mg/dL Intralipid®). removed from aliquots by or reagent. analytes determined native, lipemic after removal. bias concentration native sample calculated each parameter concentrations, 300 respectively. Also, recovery processing using calculated. biases test recoveries compared desirable specification imprecision (DSI) according Ricos available at Wesgard's website. procalcitonin DSI Barassi colleagues. Results exceeded 300 mg/L creatinine, glucose, total protein, iron albumin; all previously mentioned parameters including CK-MB, sodium, potassium, chlorides, magnesium ALP 500 mg/L Intralipid®. For criteria not met calcium, sodium chlorides phosphates, magnesium, ALP, GGT, albumin troponin T LipoClear®. Conclusions is suitable designated albumin, CRP measurements. High should be used instead TnT