Self-assembled peptide-polymer conjugates as vaccines

摘要: Peptide-based vaccines overcome most side effects associated with classical and elicit a very specific immune response. However, peptides itself are poor immunogens must be delivered an immunostimulant to achieve the desired Very few adjuvants available for vaccine formulation because known (usually pathogen-derived) too toxic human use. Therefore delivery system is required immunogenicity of without causing effects. Recently, polymer-based strategy peptide was proposed. The platform described herein able induce both humoral cellular immunity against short epitopes target either Group A Streptococcus infection or cervical cancer.