Seizures and dementia in the elderly: Nationwide Inpatient Sample 1999–2008

作者: Dean Sherzai , Travis Losey , Sonia Vega , Ayesha Sherzai

DOI: 10.1016/J.YEBEH.2014.04.015

关键词: Alzheimer s dementiaEpilepsyPsychiatryDementiaElderly populationIncidence (epidemiology)ConfoundingMultivariate logistic regression modelInternal medicineMedicine

摘要: Abstract Objectives This study aimed to examine the association between incidence of admission for a primary diagnosis “seizure” or “epilepsy” and dementia in nationally representative database, Nationwide Inpatient Sample, among elderly population (55 years age above) determine whether this relationship is different individuals with Alzheimer's versus those non-Alzheimer's dementia. Methods Data were obtained from Sample using appropriate ICD-9 codes. Frequencies descriptive analysis adjusting influence comorbidities confounders utilized. A multivariate logistic regression model adjusted age, gender, race was used further explore relationship. Results Those AD had higher risk developing seizures epilepsy (OR = 3.07, 95% CI = 2.98–3.16) as compared cases NAD (OR = 2.20, CI = 2.14–2.27). After increased patients (OR = 4.065, CI = 3.95–4.17) but not appreciably (OR = 2.68, CI = 2.60–2.75). Adding gender did change either NAD. Further adjustment African-American seizure (OR = 3.96, CI = 3.854–4.077) well (OR = 2.652, CI = 2.575–2.731). Similarly, Hispanic significantly (OR = 4.1, CI = 4.01–4.25) (OR = 2.65, CI = 2.56–2.74). Conclusion Patients have prevalence Younger more likely seizures. Race, when analyzed whole separately race, alter

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