Ketone durch basenkatalysierte Autoxydation von Aldehyden

作者: Wolfgang Sucrow

DOI: 10.1002/CBER.19671000130

关键词: ChemistryMedicinal chemistry

摘要: Der Abbau von 20-Formyl-steroiden mit Sauerstoff und Kalium-tert.-butylat bzw. Kalium-hydroxid in tert.-Butylalkohol bietet eine einfache Darstellungsmoglichkeit fur Progesteron einige Pregnanolon-Derivate.

参考文章(13)
John W. Huffman, R. P. Elliott, The Deamination of erythro- and threo-1,2-Diphenyl-2-aminoethanol1 Journal of Organic Chemistry. ,vol. 30, pp. 365- 367 ,(1965) , 10.1021/JO01013A013
W. von E. Doering, Ruth Margot Haines, Alkoxide-catalyzed Autoxidative Cleavage of Ketones and Esters1 Journal of the American Chemical Society. ,vol. 76, pp. 482- 486 ,(1954) , 10.1021/JA01631A044
Kiyoshi Sakai, Kyosuke Tsuda, Untersuchungen uber Steroide. XXIX. Versuche zur Synthese von Cholesta-7, 22-dien-3β-ol. Chemical & Pharmaceutical Bulletin. ,vol. 11, pp. 529- 530 ,(1963) , 10.1248/CPB.11.529
F. W. Heyl, M. E. Herr, Progesterone from 3-Acetoxybisnor-5-cholenaldehyde and 3-Ketobisnor-4-cholenaldehyde Journal of the American Chemical Society. ,vol. 72, pp. 2617- 2619 ,(1950) , 10.1021/JA01162A076
Douglas O. Dean, William B. Dickinson, George B. Hoey, Chas. T. Lester, sym-Tetraphenylacetone. II. Its Reactions and Derivatives Journal of the American Chemical Society. ,vol. 76, pp. 4988- 4989 ,(1954) , 10.1021/JA01648A070
A. Schöberl, Die Organische Analyse Analytica Chimica Acta. ,vol. 13, pp. 100- ,(1955) , 10.1016/S0003-2670(00)87908-8
F. W. Heyl, A. P. Centolella, M. E. Herr, Derivatives of bisnor-5-cholenaldehyde. Journal of the American Chemical Society. ,vol. 69, pp. 1957- 1961 ,(1947) , 10.1021/JA01200A035
M. E. Herr, F. W. Heyl, “Enamine” Derivatives of Steroidal Carbonyl Compounds. I Journal of the American Chemical Society. ,vol. 74, pp. 1918- 1920 ,(1952) , 10.1021/JA01134A048