Ganglionar nervous cells and telocytes in the pancreas of Octodon degus

摘要: This study shows for the first time presence of intra and extrapancreatic ganglionar neurons telocytes in Octodon degus such as those described human guinea pig pancreas. Pancreatic were identified by their histological characteristics well positive immunostaining with mouse anti-human neuron specific enolase (NSE) antibody. Somatostatin secreting delta cells (D cells) islets Langerhans rabbit antihuman polyclonal somatostatin Electron microscopy evidenced some unmyelinated axons interlobular spaces or septa, usually located adjacent to blood vessels exocrine epithelial ducts. The at least 2 telopodes was observed space, frequently close spatial relationship nerve endings. Telocytes often vicinity even proximity both secretory acini ducts regulatory nerves vessel apparatuses. A possible framework has been put forward within which structures might contribute elicit physiological responses Further studies synaptic interactions between pancreatic are needed help clarify morphological results reported here. broad overview field neurogastroenterology focus on pancreas O. related enteric nervous system (ENS) is provided order design future connections forming pathways, neurotransmission processes how disruption these pathways may disease.