Malignancy in primary biliary cirrhosis. High incidence of breast cancer in affected women

作者: Anita M. Wolke , Fenton Schaffner , Barbara Kapelman , Henry S. Sacks

DOI: 10.1016/0002-9343(84)90861-1

关键词: Breast cancerIncidence (epidemiology)Primary biliary cirrhosisRheumatoid arthritisPathologyInternal medicineHepatocellular carcinomaSclerodermaMedicineGastroenterologyHumoral immunityMalignancy

摘要: Abstract Primary biliary cirrhosis is characterized by abnormalities in both cellular and humoral immunity. It associated with presumably autoimmune diseases such as Sjogren's syndrome, rheumatoid arthritis, scleroderma. syndrome scleroderma have been noted to an increased frequency of malignancy. Of 208 patients primary cirrhosis, followed for one month 15.9 years, extrahepatic malignancies developed 11, six whom were women breast cancer, hepatocellular carcinoma. The incidence cancer was 4.4 times (p

参考文章(23)
Stephen T. O'Brien, Winston M. Eddy, Edward L. Krawitt, Primary biliary cirrhosis associated with scleroderma. Gastroenterology. ,vol. 62, pp. 118- 121 ,(1972) , 10.1016/S0016-5085(72)80017-9
Alfredo Viteri, Salvatore J. Vernace, Fenton Schaffner, EXTRAHEPATIC MALIGNANCY IN CHRONIC LIVER DISEASE: REPORT OF SIX CASES Gastroenterology. ,vol. 71, pp. 1075- 1078 ,(1976) , 10.1016/S0016-5085(76)80062-5
P J Johnson, N Krasner, B Portmann, A L Eddleston, R Williams, Hepatocellular carcinoma in Great Britain: influence of age, sex, HBsAg status, and aetiology of underlying cirrhosis. Gut. ,vol. 19, pp. 1022- 1026 ,(1978) , 10.1136/GUT.19.11.1022
Robert B. Lewis, C. William Castor, Robert E. Knisley, Giles G. Bole, Frequency of neoplasia in systemic lupus erythematosus and rheumatoid arthritis. Arthritis & Rheumatism. ,vol. 19, pp. 1256- 1260 ,(1976) , 10.1002/ART.1780190605
R.A. Fox, P.J. Scheuer, D.G. James, O. Sharma, Sheila Sherlock, IMPAIRED DELAYED HYPERSENSITIVITY IN PRIMARY BILIARY CIRRHOSIS The Lancet. ,vol. 293, pp. 959- 962 ,(1969) , 10.1016/S0140-6736(69)91860-1
R. N. M. MacSween, A clinicopathological review of 100 cases of primary malignant tumours of the liver. Journal of Clinical Pathology. ,vol. 27, pp. 669- 682 ,(1974) , 10.1136/JCP.27.8.669
D L Child, J A Mathews, R P Thompson, Arthritis and primary biliary cirrhosis. BMJ. ,vol. 2, pp. 557- 557 ,(1977) , 10.1136/BMJ.2.6086.557
DONATO ALARCÓN-SEGOVIA, EFRAIN DÍAZ-JOUANEN, EUGENIA FISHBEIN, Features of Sjögren's Syndrome in Primary Biliary Cirrhosis Annals of Internal Medicine. ,vol. 79, pp. 31- 36 ,(1973) , 10.7326/0003-4819-79-1-31