Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT).
作者： Elisa Lozano , Maria J. Monte , Oscar Briz , Angel Hernández-Hernández , Jesus M. Banales
DOI: 10.1016/J.JCONREL.2015.08.022
关键词: Toxicity 、 Ursodeoxycholic acid 、 Targeted drug delivery 、 In vitro 、 Bile acid 、 Cisplatin 、 Symporter 、 In vivo 、 Biology 、 Pharmacology
摘要: … vector pWPI-ASBT, encoding both ASBT and eGFP or simply pWPI (to generate “empty vectors”), and … Lentiviral vectors were added to target cells at a multiplicity of infection (MOI) of 25 …
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