Changes in Cholinesterase Activity in Blood of Adolescent with Metabolic Syndrome after Supplementation with Extract from Aronia melanocarpa

作者: Piotr Duchnowicz , Anna Ziobro , Elżbieta Rapacka , Maria Koter-Michalak , Bożena Bukowska

DOI: 10.1155/2018/5670145

关键词: EndocrinologyAronia melanocarpaLipid peroxidationAcetylcholinesteraseInternal medicineCholinesteraseCholesterolLipid metabolismButyrylcholinesteraseMetabolic syndromeMedicine

摘要: Obesity and metabolic syndrome (MetS) are growing problems among children adolescents. There no reports of changes in the activity butyrylcholinesterase (BChE) adolescents with especially after supplementation extract from Aronia melanocarpa. Materials studied included plasma erythrocytes isolated peripheral blood patients MetS healthy subjects. We have estimated following parameters: acetylcholinesterase (AChE) activity, lipid peroxidation lipids levels plasma, membrane. In MetS, a significant increase AChE BChE higher LDL-cholesterol triacylglycerol levels, lower HDL-cholesterol level were observed. Supplementation A. melanocarpa resulted mild but statistically reduction total cholesterol, LDL-cholesterol, caused an decrease MetS. Additionally, cholesterol erythrocyte membranes noted. Summarizing, disruption metabolism After extract, oxidative stress was

参考文章(56)
Jiří Patočka, Kamil Kuča, Daniel Jun, Acetylcholinesterase and butyrylcholinesterase--important enzymes of human body. Acta Medica. ,vol. 47, pp. 215- 228 ,(2004) , 10.14712/18059694.2018.95
Maria Koter-Michalak, Piotr Duchnowicz, Marlena Broncel, Joanna Sikora, Marzena Kozirog, Julita Chojnowska-Jezierska, Aronia melanocarpa extract reduces blood pressure, serum endothelin, lipid, and oxidative stress marker levels in patients with metabolic syndrome. Medical Science Monitor. ,vol. 16, ,(2010)
Bożena Bukowska, Paulina Sicińska, Aneta Pająk, Aneta Koceva-Chyla, Tadeusz Pietras, Anna Pszczółkowska, Paweł Górski, Maria Koter-Michalak, Oxidative stress and damage to erythrocytes in patients with chronic obstructive pulmonary disease — changes in ATPase and acetylcholinesterase activity Biochemistry and Cell Biology. ,vol. 93, pp. 574- 580 ,(2015) , 10.1139/BCB-2015-0066
Edward Kim, Morris Goldberg, Serum Cholesterol Assay Using a Stable Liebermann-Burchard Reagent Clinical Chemistry. ,vol. 15, pp. 1171- 1179 ,(1969) , 10.1093/CLINCHEM/15.12.1171
Mauro M. Cwiertnia, Vânia M. Alcântara, Rosângela R. Réa, Ana Cristina R. A. Faria, Geraldo Picheth, Marileia Scartezini, Lorena E. Graef, Marciane Welter, Butyrylcholinesterase and diabetes mellitus in the CHE2 C5- and CHE2 C5+ phenotypes Arquivos Brasileiros De Endocrinologia E Metabologia. ,vol. 54, pp. 60- 67 ,(2010) , 10.1590/S0004-27302010000100011
Jovana Karoline Lima, Neiva Leite, Luciane Viater Turek, Ricardo Lehtonen Rodrigues Souza, Luciana da Silva Timossi, Ana Claudia Vecchi Osiecki, Raul Osiecki, Lupe Furtado-Alle, 1914G variant of BCHE gene associated with enzyme activity, obesity and triglyceride levels. Gene. ,vol. 532, pp. 24- 26 ,(2013) , 10.1016/J.GENE.2013.08.068
George L. Ellman, K.Diane Courtney, Valentino Andres, Robert M. Featherstone, A new and rapid colorimetric determination of acetylcholinesterase activity Biochemical Pharmacology. ,vol. 7, pp. 88- 95 ,(1961) , 10.1016/0006-2952(61)90145-9
Catherine Rice-Evans, Nicholas Miller, George Paganga, Antioxidant properties of phenolic compounds Trends in Plant Science. ,vol. 2, pp. 152- 159 ,(1997) , 10.1016/S1360-1385(97)01018-2