Features of in vitro and in vivo behaviour of magnesium alloy WE43
作者： Elena Lukyanova , Natalia Anisimova , Natalia Martynenko , Mikhail Kiselevsky , Sergey Dobatkin
DOI: 10.1016/J.MATLET.2017.12.125
关键词: Biocompatibility 、 Biophysics 、 In vitro 、 Lysis 、 Subcutaneous implantation 、 In vivo 、 Magnesium alloy 、 Biodegradation 、 Materials science 、 Mesenchymal stem cell
摘要: Abstract Biocompatibility of magnesium alloy WE43 was investigated under in vitro and vivo conditions. The biodegradation samples found to occur very rapidly. evolution a significant amount hydrogen as product prevented the attachment cells sample surface caused their likely damage. A tendency lysis red blood drop index survival mesenchymal stromal were observed. By contrast, vivo, after subcutaneous implantation mice, rate significantly lower no sizeable generation occurred. An intimate contact between surrounding tissue formed without damage tissue, with occurrence neoangiogenesis area. Importantly, morphological studies showed that major detrimental systemic effects associated mice.
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