Neurostimulation. A promising therapeutic option for medically refractory epilepsy.

摘要: Epilepsy is a common and serious chronic neurological disorder, affecting around 65 million people worldwide. Despite the advances in pharmacologic treatments for epilepsy, approximately 30% of patients remain medically refractory continue to have seizures on medications, such cases, other treatment approaches are necessary. Resection surgery can be an alternative many achieve good seizure control; however, not all suitable candidates surgery. Electrical stimulation brain rapidly evolving therapy with uncontrolled despite best medical surgical treatment. Vagus nerve stimulation, deep anterior nucleus thalamus, responsive neurostimulation class I evidence supporting their use intractable epilepsy. In this review, we discuss these therapeutic modalities, mechanism action, efficacy, outcome, application clinical use.